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    Oncogenic impact of human papilloma virus in head and neck cancer.

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    Authors
    Heffernan, C B
    O'Neill, J P
    Timon, C
    Affiliation
    The Royal Victoria Eye and Ear Hospital, Adelaide Road, Dublin, Ireland., Heffernan_colleen@hotmail.com
    Issue Date
    2012-02-01T10:40:17Z
    MeSH
    Adolescent
    Adult
    Carcinoma, Squamous Cell/epidemiology/*virology
    Child
    Female
    *Human papillomavirus 16/genetics/immunology
    *Human papillomavirus 18/genetics/immunology
    Humans
    Male
    Mucous Membrane/virology
    Oropharyngeal Neoplasms/epidemiology/*virology
    Papillomavirus Infections/complications/epidemiology/*prevention & control
    *Papillomavirus Vaccines/immunology
    Prevalence
    Risk Factors
    Sexual Behavior
    Sexually Transmitted Diseases, Viral/complications/epidemiology
    Uterine Cervical Neoplasms/prevention & control/virology
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    Citation
    J Laryngol Otol. 2010 Sep;124(9):941-4. Epub 2010 Jun 2.
    Journal
    The Journal of laryngology and otology
    URI
    http://hdl.handle.net/10147/207756
    DOI
    10.1017/S0022215110001179
    PubMed ID
    20519038
    Abstract
    There is considerable debate within the literature about the significance of human papilloma virus in head and neck squamous cell carcinoma, and its potential influence on the prevention, diagnosis, grading, treatment and prognosis of these cancers. Cigarette smoking and alcohol consumption have traditionally been cited as the main risk factors for head and neck cancers. However, human papilloma virus, normally associated with cervical and other genital carcinomas, has emerged as a possible key aetiological factor in head and neck squamous cell carcinoma, especially oropharyngeal cancers. These cancers pose a significant financial burden on health resources and are increasing in incidence. The recent introduction of vaccines targeted against human papilloma virus types 16 and 18, to prevent cervical cancer, has highlighted the need for ongoing research into the importance of human papilloma virus in head and neck squamous cell carcinoma.
    Language
    eng
    ISSN
    1748-5460 (Electronic)
    0022-2151 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1017/S0022215110001179
    Scopus Count
    Collections
    Royal Victoria Eye and Ear Hospital

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