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dc.contributor.authorCooley, Sharon M
dc.contributor.authorDonnelly, Jennifer C
dc.contributor.authorWalsh, Thomas
dc.contributor.authorMacMahon, Corrina
dc.contributor.authorGillan, John
dc.contributor.authorGeary, Michael P
dc.date.accessioned2012-02-01T10:37:49Z
dc.date.available2012-02-01T10:37:49Z
dc.date.issued2012-02-01T10:37:49Z
dc.identifier.citationJ Perinat Med. 2011 Mar;39(2):143-9. Epub 2010 Dec 3.en_GB
dc.identifier.issn1619-3997 (Electronic)en_GB
dc.identifier.issn0300-5577 (Linking)en_GB
dc.identifier.pmid21126220en_GB
dc.identifier.doi10.1515/JPM.2010.130en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207715
dc.description.abstractAIMS: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease.
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshDelivery, Obstetricen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshGravidityen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshInfant, Small for Gestational Ageen_GB
dc.subject.meshLabor, Obstetricen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPregnancyen_GB
dc.subject.meshPregnancy Complications/etiology/ultrasonographyen_GB
dc.subject.meshPregnancy Outcomeen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshRisk Factorsen_GB
dc.subject.meshUltrasonography, Doppler, Coloren_GB
dc.subject.meshUltrasonography, Prenatalen_GB
dc.subject.meshUmbilical Arteries/*ultrasonographyen_GB
dc.subject.meshUterine Artery/*ultrasonographyen_GB
dc.subject.meshYoung Adulten_GB
dc.titleThe impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population.en_GB
dc.contributor.departmentDepartment of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland., smcooley@hotmail.comen_GB
dc.identifier.journalJournal of perinatal medicineen_GB
dc.description.provinceLeinster
html.description.abstractAIMS: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease.


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