The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population.
dc.contributor.author | Cooley, Sharon M | |
dc.contributor.author | Donnelly, Jennifer C | |
dc.contributor.author | Walsh, Thomas | |
dc.contributor.author | MacMahon, Corrina | |
dc.contributor.author | Gillan, John | |
dc.contributor.author | Geary, Michael P | |
dc.date.accessioned | 2012-02-01T10:37:49Z | |
dc.date.available | 2012-02-01T10:37:49Z | |
dc.date.issued | 2012-02-01T10:37:49Z | |
dc.identifier.citation | J Perinat Med. 2011 Mar;39(2):143-9. Epub 2010 Dec 3. | en_GB |
dc.identifier.issn | 1619-3997 (Electronic) | en_GB |
dc.identifier.issn | 0300-5577 (Linking) | en_GB |
dc.identifier.pmid | 21126220 | en_GB |
dc.identifier.doi | 10.1515/JPM.2010.130 | en_GB |
dc.identifier.uri | http://hdl.handle.net/10147/207715 | |
dc.description.abstract | AIMS: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease. | |
dc.language.iso | eng | en_GB |
dc.subject.mesh | Adolescent | en_GB |
dc.subject.mesh | Adult | en_GB |
dc.subject.mesh | Delivery, Obstetric | en_GB |
dc.subject.mesh | Female | en_GB |
dc.subject.mesh | Gravidity | en_GB |
dc.subject.mesh | Humans | en_GB |
dc.subject.mesh | Infant, Newborn | en_GB |
dc.subject.mesh | Infant, Small for Gestational Age | en_GB |
dc.subject.mesh | Labor, Obstetric | en_GB |
dc.subject.mesh | Male | en_GB |
dc.subject.mesh | Pregnancy | en_GB |
dc.subject.mesh | Pregnancy Complications/etiology/ultrasonography | en_GB |
dc.subject.mesh | Pregnancy Outcome | en_GB |
dc.subject.mesh | Retrospective Studies | en_GB |
dc.subject.mesh | Risk Factors | en_GB |
dc.subject.mesh | Ultrasonography, Doppler, Color | en_GB |
dc.subject.mesh | Ultrasonography, Prenatal | en_GB |
dc.subject.mesh | Umbilical Arteries/*ultrasonography | en_GB |
dc.subject.mesh | Uterine Artery/*ultrasonography | en_GB |
dc.subject.mesh | Young Adult | en_GB |
dc.title | The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population. | en_GB |
dc.contributor.department | Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland., smcooley@hotmail.com | en_GB |
dc.identifier.journal | Journal of perinatal medicine | en_GB |
dc.description.province | Leinster | |
html.description.abstract | AIMS: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease. |