AffiliationDepartment of Dermatology, St Vincent's University Hospital, Dublin, Ireland., firstname.lastname@example.org
Killer Cells, Natural/*immunology
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CitationJ Innate Immun. 2011;3(4):403-10. Epub 2011 May 25.
JournalJournal of innate immunity
AbstractPsoriasis is one of the most common immune-mediated disorders. There is evidence that it is mediated by Th1 and, more recently, Th17 cells. The cytokine pattern, particularly the dominance of TNF-alpha, implicates the innate immune system in psoriasis pathogenesis. Of the many components of the innate immune system known to be involved in psoriatic lesions, natural killer and natural killer T cells appear to have a unique role. We review the evidence supporting a role for natural killer cells in psoriasis.