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    Subclinical hypothyroidism in childhood.

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    Authors
    O'Grady, M J
    Cody, D
    Affiliation
    Department of Endocrinology and Diabetes, Our Ladys Childrens Hospital, Crumlin, , Dublin, Ireland.
    Issue Date
    2012-02-01T10:24:24Z
    MeSH
    Child
    Child, Preschool
    Down Syndrome/complications
    Genetic Predisposition to Disease
    Hormone Replacement Therapy/methods
    Humans
    Hypothyroidism/*diagnosis/drug therapy/etiology
    Infant
    Infant, Newborn
    Thyrotropin/blood
    Thyroxine/therapeutic use
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    Citation
    Arch Dis Child. 2011 Mar;96(3):280-4. Epub 2010 Apr 22.
    Journal
    Archives of disease in childhood
    URI
    http://hdl.handle.net/10147/207414
    DOI
    10.1136/adc.2009.181800
    PubMed ID
    20413616
    Abstract
    Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.
    Language
    eng
    ISSN
    1468-2044 (Electronic)
    0003-9888 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1136/adc.2009.181800
    Scopus Count
    Collections
    Children's Health Ireland (CHI) at Crumlin

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