Subclinical hypothyroidism in childhood.

Authors
O'Grady, M J
Cody, D
Affiliation
Department of Endocrinology and Diabetes, Our Ladys Childrens Hospital, Crumlin, , Dublin, Ireland.
Issue Date
2012-02-01T10:24:24Z
MeSH
Child
Child, Preschool
Down Syndrome/complications
Genetic Predisposition to Disease
Hormone Replacement Therapy/methods
Humans
Hypothyroidism/*diagnosis/drug therapy/etiology
Infant
Infant, Newborn
Thyrotropin/blood

Metadata
Show full item record
Citation
Arch Dis Child. 2011 Mar;96(3):280-4. Epub 2010 Apr 22.
Journal
Archives of disease in childhood
URI
http://hdl.handle.net/10147/207414
DOI
10.1136/adc.2009.181800
PubMed ID
20413616
Abstract
Subclinical hypothyroidism (SH) is defined as an elevated thyroid stimulating hormone (TSH) in association with a normal total or free thyroxine (T4) or triiodothyronine (T3). It is frequently encountered in both neonatology and general paediatric practice; however, its clinical significance is widely debated. Currently there is no broad consensus on the investigation and treatment of these patients; specifically who to treat and what cut-off level of TSH should be used. This paper reviews the available evidence regarding investigation, treatments and outcomes reported for childhood SH.
Language
eng
ISSN
1468-2044 (Electronic)
0003-9888 (Linking)
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