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dc.contributor.authorO'Gorman, Clodagh S
dc.contributor.authorTortoriello, Tia A
dc.contributor.authorMcMahon, Colin J
dc.date.accessioned2012-02-01T10:23:42Z
dc.date.available2012-02-01T10:23:42Z
dc.date.issued2012-02-01T10:23:42Z
dc.identifier.citationPediatr Cardiol. 2009 May;30(4):426-30. Epub 2009 Mar 26.en_GB
dc.identifier.issn1432-1971 (Electronic)en_GB
dc.identifier.issn0172-0643 (Linking)en_GB
dc.identifier.pmid19322603en_GB
dc.identifier.doi10.1007/s00246-009-9410-9en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207387
dc.description.abstractAlthough single individual reports have documented outcomes in children with pentalogy of are few data available for postoperative outcome of this cohort of patients after cardiac surgery. The aim of this study was to retrospectively review the clinical details of patients with pentalogy of Cantrell managed at two centers. Two cardiac surgical institutions retrospectively studied all patients with pentalogy of Cantrell and significant congenital heart disease who underwent surgical intervention, excluding PDA ligation, between 1992 and 2004. Seven children with pentalogy of Cantrell underwent surgical intervention at a median age of 60 days (range, 1-11 months). Three patients had tetralogy of Fallot, two double outlet right ventricle, one patient had tricuspid atresia, and one patient a perimembranous ventricular septal defect. The mean duration of postoperative ventilation was 112.8 days (range, 4-335 days) but three patients required ventilation for more than 100 days. Patients who had a preoperative diaphragmatic plication required a longer duration of ventilation (mean = 186.5 days [range, 100-273 days] compared with mean = 132 days [range, 4-335 days]). Four patients survived, with three patients weaned from ventilation. Three patients had withdrawal of care following failure to wean from ventilation, following multisystem organ failure, and at the request of their parents. In conclusion, the postoperative care of children with pentalogy of Cantrell after cardiac surgery is often complicated by prolonged need for ventilatory support and multiple postoperative complications. Earlier surgical intervention does not necessarily reduce morbidity and mortality. These data may help in the counseling of parents prior to surgical intervention.
dc.language.isoengen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHeart Defects, Congenital/*mortality/*surgeryen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfanten_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshMaleen_GB
dc.subject.meshPostoperative Complicationsen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.titleOutcome of children with Pentalogy of Cantrell following cardiac surgery.en_GB
dc.contributor.departmentDepartment of Cardiology, Our Lady's Children's Hospital, Crumlin, Dublin 12,, Ireland.en_GB
dc.identifier.journalPediatric cardiologyen_GB
dc.description.provinceLeinster
html.description.abstractAlthough single individual reports have documented outcomes in children with pentalogy of are few data available for postoperative outcome of this cohort of patients after cardiac surgery. The aim of this study was to retrospectively review the clinical details of patients with pentalogy of Cantrell managed at two centers. Two cardiac surgical institutions retrospectively studied all patients with pentalogy of Cantrell and significant congenital heart disease who underwent surgical intervention, excluding PDA ligation, between 1992 and 2004. Seven children with pentalogy of Cantrell underwent surgical intervention at a median age of 60 days (range, 1-11 months). Three patients had tetralogy of Fallot, two double outlet right ventricle, one patient had tricuspid atresia, and one patient a perimembranous ventricular septal defect. The mean duration of postoperative ventilation was 112.8 days (range, 4-335 days) but three patients required ventilation for more than 100 days. Patients who had a preoperative diaphragmatic plication required a longer duration of ventilation (mean = 186.5 days [range, 100-273 days] compared with mean = 132 days [range, 4-335 days]). Four patients survived, with three patients weaned from ventilation. Three patients had withdrawal of care following failure to wean from ventilation, following multisystem organ failure, and at the request of their parents. In conclusion, the postoperative care of children with pentalogy of Cantrell after cardiac surgery is often complicated by prolonged need for ventilatory support and multiple postoperative complications. Earlier surgical intervention does not necessarily reduce morbidity and mortality. These data may help in the counseling of parents prior to surgical intervention.


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