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    Outcome of children with Pentalogy of Cantrell following cardiac surgery.

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    Authors
    O'Gorman, Clodagh S
    Tortoriello, Tia A
    McMahon, Colin J
    Affiliation
    Department of Cardiology, Our Lady's Children's Hospital, Crumlin, Dublin 12,, Ireland.
    Issue Date
    2012-02-01T10:23:42Z
    MeSH
    Female
    Heart Defects, Congenital/*mortality/*surgery
    Humans
    Infant
    Infant, Newborn
    Male
    Postoperative Complications
    Retrospective Studies
    Treatment Outcome
    
    Metadata
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    Citation
    Pediatr Cardiol. 2009 May;30(4):426-30. Epub 2009 Mar 26.
    Journal
    Pediatric cardiology
    URI
    http://hdl.handle.net/10147/207387
    DOI
    10.1007/s00246-009-9410-9
    PubMed ID
    19322603
    Abstract
    Although single individual reports have documented outcomes in children with pentalogy of are few data available for postoperative outcome of this cohort of patients after cardiac surgery. The aim of this study was to retrospectively review the clinical details of patients with pentalogy of Cantrell managed at two centers. Two cardiac surgical institutions retrospectively studied all patients with pentalogy of Cantrell and significant congenital heart disease who underwent surgical intervention, excluding PDA ligation, between 1992 and 2004. Seven children with pentalogy of Cantrell underwent surgical intervention at a median age of 60 days (range, 1-11 months). Three patients had tetralogy of Fallot, two double outlet right ventricle, one patient had tricuspid atresia, and one patient a perimembranous ventricular septal defect. The mean duration of postoperative ventilation was 112.8 days (range, 4-335 days) but three patients required ventilation for more than 100 days. Patients who had a preoperative diaphragmatic plication required a longer duration of ventilation (mean = 186.5 days [range, 100-273 days] compared with mean = 132 days [range, 4-335 days]). Four patients survived, with three patients weaned from ventilation. Three patients had withdrawal of care following failure to wean from ventilation, following multisystem organ failure, and at the request of their parents. In conclusion, the postoperative care of children with pentalogy of Cantrell after cardiac surgery is often complicated by prolonged need for ventilatory support and multiple postoperative complications. Earlier surgical intervention does not necessarily reduce morbidity and mortality. These data may help in the counseling of parents prior to surgical intervention.
    Language
    eng
    ISSN
    1432-1971 (Electronic)
    0172-0643 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00246-009-9410-9
    Scopus Count
    Collections
    Children's Health Ireland (CHI) at Crumlin

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