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dc.contributor.authorOwens, C
dc.contributor.authorMannion, D
dc.contributor.authorO'Marcaigh, A
dc.contributor.authorWaldron, M
dc.contributor.authorButler, K
dc.contributor.authorO'Meara, A
dc.date.accessioned2012-02-01T10:23:34Z
dc.date.available2012-02-01T10:23:34Z
dc.date.issued2012-02-01T10:23:34Z
dc.identifier.citationIr J Med Sci. 2011 Mar;180(1):85-9. Epub 2010 Nov 10.en_GB
dc.identifier.issn1863-4362 (Electronic)en_GB
dc.identifier.issn0021-1265 (Linking)en_GB
dc.identifier.pmid21063805en_GB
dc.identifier.doi10.1007/s11845-010-0634-8en_GB
dc.identifier.urihttp://hdl.handle.net/10147/207382
dc.description.abstractBACKGROUND: Overall survival in paediatric cancer has improved significantly over the past 20 years. Treatment strategies have been intensified, and supportive care has made substantial advances. Historically, paediatric oncology patients admitted to an intensive care unit (ICU) have had extremely poor outcomes. METHODS: We conducted a retrospective cohort study over a 3-year period in a single centre to evaluate the outcomes for this particularly vulnerable group of patients admitted to a paediatric ICU. RESULTS: Fifty-five patients were admitted a total of 66 times to the ICU during the study period. The mortality rate of this group was 23% compared with an overall ICU mortality rate of 5%. 11/15 patients who died had an underlying haematological malignancy. Twenty-eight percent of children with organism-identified sepsis died. CONCLUSIONS: While mortality rates for paediatric oncology patients admitted to a ICU have improved, they are still substantial. Those with a haematological malignancy or admitted with sepsis are most at risk.
dc.language.isoengen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshBrain Neoplasms/mortalityen_GB
dc.subject.meshChilden_GB
dc.subject.meshChild, Preschoolen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHematologic Neoplasms/*mortality/*therapyen_GB
dc.subject.meshHumansen_GB
dc.subject.meshInfanten_GB
dc.subject.meshInfant, Newbornen_GB
dc.subject.meshIntensive Care Units, Pediatric/statistics & numerical dataen_GB
dc.subject.meshIreland/epidemiologyen_GB
dc.subject.meshMaleen_GB
dc.subject.meshNeoplasms/*mortality/*therapyen_GB
dc.subject.meshNeuroblastoma/mortality/therapyen_GB
dc.subject.meshPrecursor Cell Lymphoblastic Leukemia-Lymphoma/mortality/therapyen_GB
dc.subject.meshRetrospective Studiesen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.titleIndications for admission, treatment and improved outcome of paediatric haematology/oncology patients admitted to a tertiary paediatric ICU.en_GB
dc.contributor.departmentDepartment of Haematology/Oncology, Our Lady's Children's Hospital, Crumlin,, Dublin, Ireland. cormacowens@yahoo.comen_GB
dc.identifier.journalIrish journal of medical scienceen_GB
dc.description.provinceLeinster
html.description.abstractBACKGROUND: Overall survival in paediatric cancer has improved significantly over the past 20 years. Treatment strategies have been intensified, and supportive care has made substantial advances. Historically, paediatric oncology patients admitted to an intensive care unit (ICU) have had extremely poor outcomes. METHODS: We conducted a retrospective cohort study over a 3-year period in a single centre to evaluate the outcomes for this particularly vulnerable group of patients admitted to a paediatric ICU. RESULTS: Fifty-five patients were admitted a total of 66 times to the ICU during the study period. The mortality rate of this group was 23% compared with an overall ICU mortality rate of 5%. 11/15 patients who died had an underlying haematological malignancy. Twenty-eight percent of children with organism-identified sepsis died. CONCLUSIONS: While mortality rates for paediatric oncology patients admitted to a ICU have improved, they are still substantial. Those with a haematological malignancy or admitted with sepsis are most at risk.


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