Indications for admission, treatment and improved outcome of paediatric haematology/oncology patients admitted to a tertiary paediatric ICU.
Affiliation
Department of Haematology/Oncology, Our Lady's Children's Hospital, Crumlin,, Dublin, Ireland. cormacowens@yahoo.comIssue Date
2012-02-01T10:23:34ZMeSH
AdolescentBrain Neoplasms/mortality
Child
Child, Preschool
Female
Hematologic Neoplasms/*mortality/*therapy
Humans
Infant
Infant, Newborn
Intensive Care Units, Pediatric/statistics & numerical data
Ireland/epidemiology
Male
Neoplasms/*mortality/*therapy
Neuroblastoma/mortality/therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma/mortality/therapy
Retrospective Studies
Treatment Outcome
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Show full item recordCitation
Ir J Med Sci. 2011 Mar;180(1):85-9. Epub 2010 Nov 10.Journal
Irish journal of medical scienceDOI
10.1007/s11845-010-0634-8PubMed ID
21063805Abstract
BACKGROUND: Overall survival in paediatric cancer has improved significantly over the past 20 years. Treatment strategies have been intensified, and supportive care has made substantial advances. Historically, paediatric oncology patients admitted to an intensive care unit (ICU) have had extremely poor outcomes. METHODS: We conducted a retrospective cohort study over a 3-year period in a single centre to evaluate the outcomes for this particularly vulnerable group of patients admitted to a paediatric ICU. RESULTS: Fifty-five patients were admitted a total of 66 times to the ICU during the study period. The mortality rate of this group was 23% compared with an overall ICU mortality rate of 5%. 11/15 patients who died had an underlying haematological malignancy. Twenty-eight percent of children with organism-identified sepsis died. CONCLUSIONS: While mortality rates for paediatric oncology patients admitted to a ICU have improved, they are still substantial. Those with a haematological malignancy or admitted with sepsis are most at risk.Language
engISSN
1863-4362 (Electronic)0021-1265 (Linking)
ae974a485f413a2113503eed53cd6c53
10.1007/s11845-010-0634-8
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