A case of congenital solitary Langerhans cell histiocytoma.

Authors
Ricciardo, Bernadette
Irvine, Alan
McDermott, Michael
Ryan, John
Collins, Sinead
Affiliation
Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Dublin,, Ireland. berniricciardo@yahoo.com.au
Issue Date
2012-02-01T10:21:26Z
MeSH
Antigens, CD1/analysis
Face
Histiocytoma/congenital/*pathology
Histiocytosis, Langerhans-Cell/congenital/*pathology
Humans
Infant, Newborn
Male
S100 Proteins/analysis
Skin Neoplasms/genetics/*pathology

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Citation
Australas J Dermatol. 2011 May;52(2):e1-3. doi: 10.1111/j.1440-0960.2010.00625.x., Epub 2010 Feb 26.
Journal
The Australasian journal of dermatology
URI
http://hdl.handle.net/10147/207357
DOI
10.1111/j.1440-0960.2010.00625.x
PubMed ID
21605085
Abstract
A newborn baby boy was referred to the Paediatric Dermatology Unit with a solitary asymptomatic nodule overlying his right nasolabial fold. Complete physical examination, full blood count, serum chemistry, liver function tests and baseline imaging were unremarkable. Histopathological examination showed an atypical dermal infiltrate of mononuclear cells that stained positive with CD1a and S100. A diagnosis of congenital solitary Langerhans cell histiocytoma was made. The lesion completely resolved by 4 months of age. The baby is now 15 months old and repeat systemic evaluation has remained normal.
Language
eng
ISSN
1440-0960 (Electronic)
0004-8380 (Linking)
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