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    A case of congenital solitary Langerhans cell histiocytoma.

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    Authors
    Ricciardo, Bernadette
    Irvine, Alan
    McDermott, Michael
    Ryan, John
    Collins, Sinead
    Affiliation
    Department of Dermatology, Our Lady of Lourdes Hospital, Drogheda, Dublin,, Ireland. berniricciardo@yahoo.com.au
    Issue Date
    2012-02-01T10:21:26Z
    MeSH
    Antigens, CD1/analysis
    Face
    Histiocytoma/congenital/*pathology
    Histiocytosis, Langerhans-Cell/congenital/*pathology
    Humans
    Infant, Newborn
    Male
    S100 Proteins/analysis
    Skin Neoplasms/genetics/*pathology
    
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    Citation
    Australas J Dermatol. 2011 May;52(2):e1-3. doi: 10.1111/j.1440-0960.2010.00625.x., Epub 2010 Feb 26.
    Journal
    The Australasian journal of dermatology
    URI
    http://hdl.handle.net/10147/207357
    DOI
    10.1111/j.1440-0960.2010.00625.x
    PubMed ID
    21605085
    Abstract
    A newborn baby boy was referred to the Paediatric Dermatology Unit with a solitary asymptomatic nodule overlying his right nasolabial fold. Complete physical examination, full blood count, serum chemistry, liver function tests and baseline imaging were unremarkable. Histopathological examination showed an atypical dermal infiltrate of mononuclear cells that stained positive with CD1a and S100. A diagnosis of congenital solitary Langerhans cell histiocytoma was made. The lesion completely resolved by 4 months of age. The baby is now 15 months old and repeat systemic evaluation has remained normal.
    Language
    eng
    ISSN
    1440-0960 (Electronic)
    0004-8380 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1440-0960.2010.00625.x
    Scopus Count
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    Our Lady of Lourdes Hospital

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