Pituitary dysfunction following traumatic brain injury or subarachnoid haemorrhage - in "Endocrine Management in the Intensive Care Unit".
AffiliationAcademic Department of Endocrinology, Beaumont Hospital/RCSI Medical School,, Beaumont Road, Dublin 9, Ireland.
MetadataShow full item record
CitationBest Pract Res Clin Endocrinol Metab. 2011 Oct;25(5):783-98.
JournalBest practice & research. Clinical endocrinology & metabolism
AbstractTraumatic brain injury and subarachnoid haemorrhage are important causes of morbidity and mortality in the developed world. There is a large body of evidence that demonstrates that both conditions may adversely affect pituitary function in both the acute and chronic phases of recovery. Diagnosis of hypopituitarism and accurate treatment of pituitary disorders offers the opportunity to improve mortality and outcome in both traumatic brain injury and subarachnoid haemorrhage. In this article, we will review the history and pathophysiology of pituitary function in the acute phase following traumatic brain injury and subarachnoid haemorrhage, and we will discuss in detail three key aspects of pituitary dysfunction which occur in the early course of TBI; acute cortisol deficiency, diabetes insipidus and SIAD.
- Traumatic brain injury and subarachnoid haemorrhage are conditions at high risk for hypopituitarism: screening study at 3 months after the brain injury.
- Authors: Aimaretti G, Ambrosio MR, Di Somma C, Fusco A, Cannavò S, Gasperi M, Scaroni C, De Marinis L, Benvenga S, degli Uberti EC, Lombardi G, Mantero F, Martino E, Giordano G, Ghigo E
- Issue date: 2004 Sep
- Structured assessment of hypopituitarism after traumatic brain injury and aneurysmal subarachnoid hemorrhage in 1242 patients: the German interdisciplinary database.
- Authors: Schneider HJ, Schneider M, Kreitschmann-Andermahr I, Tuschy U, Wallaschofski H, Fleck S, Faust M, Renner CI, Kopczak A, Saller B, Buchfelder M, Jordan M, Stalla GK
- Issue date: 2011 Sep
- Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review.
- Authors: Schneider HJ, Kreitschmann-Andermahr I, Ghigo E, Stalla GK, Agha A
- Issue date: 2007 Sep 26
- Neuroendocrine abnormalities in patients with traumatic brain injury.
- Authors: Yuan XQ, Wade CE
- Issue date: 1991
- Evaluation of pituitary function after traumatic brain injury in childhood.
- Authors: Khadr SN, Crofton PM, Jones PA, Wardhaugh B, Roach J, Drake AJ, Minns RA, Kelnar CJ
- Issue date: 2010 Nov