AffiliationRoyal College of Surgeons in Ireland Medical School, Beaumont Hospital, Dublin,, Ireland. email@example.com
MeSHDiabetes Mellitus, Type 1/complications
Drug Resistance, Multiple, Bacterial
MetadataShow full item record
CitationFoot Ankle Spec. 2011 Feb;4(1):45-8. Epub 2010 Dec 6.
JournalFoot & ankle specialist
AbstractAlthough simultaneous pancreas and kidney transplant improves most complications of type 1 diabetes, suppression of the immune system increases the risk for infection. The authors report the case of a patient who, despite receiving a simultaneous pancreas and kidney transplant, subsequently developed neuro-ischemic ulcers of his right foot requiring repeated amputations. He then developed an infected ulcer of his remaining right big toe, with significant implications for his mobility. This ulcer proved resistant to multiple courses of antibiotics and care in a specialist foot clinic but resolved completely following a course of hyperbaric oxygen therapy. The role of hyperbaric oxygen in diabetic foot ulcers is not yet fully established but should be considered in resistant cases with vascular insufficiency and a significant infective component.