Characteristics of patients presenting with erythema nodosum and sarcoidosis.
Affiliation
Department of Respiratory Medicine, Mercy University Hospital, Cork., terryoconnor@eircom.netIssue Date
2012-01-31T16:39:10ZMeSH
AdultAge Distribution
Age Factors
Aged
Aged, 80 and over
Bronchoalveolar Lavage Fluid/*chemistry/cytology
Erythema Nodosum/epidemiology/*radiography
Female
Granuloma/epidemiology/pathology
Humans
Ireland/epidemiology
Lymphocytosis/epidemiology/*radiography
Male
Middle Aged
Peptidyl-Dipeptidase A/*blood
Retrospective Studies
Risk Factors
Sarcoidosis, Pulmonary/epidemiology/pathology/*radiography
Statistics as Topic
Young Adult
Metadata
Show full item recordCitation
Ir Med J. 2009 Jun;102(6):181-4.Journal
Irish medical journalPubMed ID
19722355Abstract
We explored the relationship between erythema nodosum (EN) and sex, age, serum angiotensin converting enzyme (ACE), bronchoalveolar lavage lymphocytosis (BAL-I), interstitial granulomas and radiological stage in patients presenting with pulmonary sarcoidosis in Ireland. Sixty-nine patients diagnosed with sarcoidosis between 2003 and 2006 were studied. Forty one patients (59%) were male. Sixteen patients (23%) presented with EN. Forty one patients of 65 (63%) had transbronchial biopsies demonstrating non-caseating granulomas. Patients with sarcoidosis presenting with EN were more likely to be female (p=0.042), younger (p=0.012) and have earlier stage pulmonary disease (p=0.02). There were no correlations between serum ACE, interstitial granulomas and disease stage. BAL-I did however predict increasing disease radiological stage (p=0.042). In this study, one quarter of patients with sarcoidosis presented with EN among their presenting features. These patients were more likely to be young females with early stage radiological disease.Language
engISSN
0332-3102 (Print)0332-3102 (Linking)
Collections
Related articles
- Angiotensin-converting enzyme. II. Serum activity in early and newly diagnosed sarcoidosis.
- Authors: Grönhagen-Riska C, Selroos O, Wägar G, Fyhrquist F
- Issue date: 1979 Apr
- [A comparative clinical analysis of thoracic sarcoidosis and multi-organ sarcoidosis].
- Authors: Jin JM, Sun YC, Zhuo J, Liu XF, Li R
- Issue date: 2011 Dec
- Relation between clinical stage of sarcoidosis and serum values of angiotensin converting enzyme and beta2-microglobulin.
- Authors: Selroos O, Klockars M
- Issue date: 1987 Mar
- Bronchoalveolar lavage fluid angiotensin-converting enzyme in interstitial lung diseases.
- Authors: Specks U, Martin WJ 2nd, Rohrbach MS
- Issue date: 1990 Jan
- Bronchoalveolar lavage fluid granulomas in a case of severe sarcoidosis.
- Authors: Hendricks MV, Crosby JH, Davis WB
- Issue date: 1999 Aug