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    Survival trends of US dialysis patients with heart failure: 1995 to 2005.

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    Authors
    Stack, Austin G
    Mohammed, Amir
    Hanley, Alan
    Mutwali, Arif
    Nguyen, Hoang
    Affiliation
    Regional Kidney Centre, Department of Medicine, Letterkenny General Hospital,, Letterkenny, Donegal, Ireland. Austin.Stack@hse.ie
    Issue Date
    2012-01-31T16:31:12Z
    MeSH
    Adolescent
    Adult
    Age Factors
    Aged
    Analysis of Variance
    Chi-Square Distribution
    Cohort Studies
    Female
    Heart Failure/*mortality
    Humans
    Kidney Failure, Chronic/*mortality/*therapy
    Logistic Models
    Male
    Middle Aged
    Odds Ratio
    Prevalence
    Proportional Hazards Models
    Renal Dialysis/*mortality
    Risk Assessment
    Risk Factors
    Sex Factors
    Survival Analysis
    Survival Rate
    Time Factors
    Treatment Outcome
    United States/epidemiology
    Young Adult
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    Citation
    Clin J Am Soc Nephrol. 2011 Aug;6(8):1982-9. Epub 2011 Jul 22.
    Journal
    Clinical journal of the American Society of Nephrology : CJASN
    URI
    http://hdl.handle.net/10147/205738
    DOI
    10.2215/CJN.01130211
    PubMed ID
    21784821
    Abstract
    BACKGROUND AND OBJECTIVES: Congestive heart failure (CHF) is a major risk factor for death in end-stage kidney disease; however, data on prevalence and survival trends are limited. The objective of this study was to determine the prevalence and mortality effect of CHF in successive incident dialysis cohorts. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: This was a population-based cohort of incident US dialysis patients (n = 926,298) from 1995 to 2005. Age- and gender-specific prevalence of CHF was determined by incident year, whereas temporal trends in mortality were compared using multivariable Cox regression. RESULTS: The prevalence of CHF was significantly higher in women than men and in older than younger patients, but it did not change over time in men (range 28% to 33%) or women (range 33% to 36%). From 1995 to 2005, incident death rates decreased for younger men (70 years). For women, the pattern was similar but less impressive. During this period, the adjusted mortality risks (relative risk [RR]) from CHF decreased in men (from RR = 1.06 95% Confidence intervals (CI) 1.02-1.11 in 1995 to 0.91 95% CI 0.87-0.96 in 2005) and women (from RR = 1.06 95% CI 1.01-1.10 in 1995 to 0.90 95% CI 0.85-0.95 in 2005 compared with referent year 2000; RR = 1.00). The reduction in mortality over time was greater for younger than older patients (20% to 30% versus 5% to 10% decrease per decade). CONCLUSIONS: Although CHF remains a common condition at dialysis initiation, mortality risks in US patients have declined from 1995 to 2005.
    Language
    eng
    ISSN
    1555-905X (Electronic)
    1555-9041 (Linking)
    ae974a485f413a2113503eed53cd6c53
    10.2215/CJN.01130211
    Scopus Count
    Collections
    Letterkenny University Hospital

    entitlement

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