Two-stage revision of infected hip arthroplasty using a shortened post-operative course of antibiotics.
Affiliation
Department of Orthopaedic Surgery, Mid-Western Regional Orthopaedic Hospital, Croom, Ireland. paul.mckenna@ul.ieIssue Date
2009-04MeSH
AdultAged
Anti-Bacterial Agents
Arthroplasty, Replacement, Hip
Bone Cements
Debridement
Female
Hip Joint
Hip Prosthesis
Humans
Length of Stay
Male
Middle Aged
Prosthesis-Related Infections
Reoperation
Retrospective Studies
Metadata
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Two-stage revision of infected hip arthroplasty using a shortened post-operative course of antibiotics. 2009, 129 (4):489-94 Arch Orthop Trauma SurgJournal
Archives of orthopaedic and trauma surgeryDOI
10.1007/s00402-008-0683-xPubMed ID
18677498Additional Links
http://www.springerlink.com/content/d14w77310l45r4v5/Abstract
We present a series of 30 consecutive patients with 31 infected total hip arthroplasties treated by a single surgeon over a 4-year period in whom a shortened post-operative course of antimicrobial chemotherapy was used.The treatment protocol consisted of a two-stage exchange with removal of infected components, insertion of an interim antibiotic eluting cement spacer and re-implantation of an extensively coated uncemented prosthesis on the femoral side. Systemic antibiotic treatment following each stage consisted of an abridged course of 5 days post-operative intra-venous administration followed by complete cessation of anti-microbial therapy.
At a mean follow-up of 35 months (minimum 24 months), there were no cases of recurrent prosthetic infection and no patient had required revision for aseptic loosening or mechanical instability on the femoral side. The combination of effective-staged surgical joint debridement, a shortened post-operative course of systemic antibiotic treatment and an adequate latent period before re-implantation has led to encourage early results in this series of revised chronic hip joint prosthetic infections.
Item Type
ArticleLanguage
enISSN
1434-3916ae974a485f413a2113503eed53cd6c53
10.1007/s00402-008-0683-x
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