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    Two-stage revision of infected hip arthroplasty using a shortened post-operative course of antibiotics.

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    Authors
    McKenna, Paul B
    O'Shea, Keiran
    Masterson, Eric L
    Affiliation
    Department of Orthopaedic Surgery, Mid-Western Regional Orthopaedic Hospital, Croom, Ireland. paul.mckenna@ul.ie
    Issue Date
    2009-04
    MeSH
    Adult
    Aged
    Anti-Bacterial Agents
    Arthroplasty, Replacement, Hip
    Bone Cements
    Debridement
    Female
    Hip Joint
    Hip Prosthesis
    Humans
    Length of Stay
    Male
    Middle Aged
    Prosthesis-Related Infections
    Reoperation
    Retrospective Studies
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    Citation
    Two-stage revision of infected hip arthroplasty using a shortened post-operative course of antibiotics. 2009, 129 (4):489-94 Arch Orthop Trauma Surg
    Journal
    Archives of orthopaedic and trauma surgery
    URI
    http://hdl.handle.net/10147/205030
    DOI
    10.1007/s00402-008-0683-x
    PubMed ID
    18677498
    Additional Links
    http://www.springerlink.com/content/d14w77310l45r4v5/
    Abstract
    We present a series of 30 consecutive patients with 31 infected total hip arthroplasties treated by a single surgeon over a 4-year period in whom a shortened post-operative course of antimicrobial chemotherapy was used.
    The treatment protocol consisted of a two-stage exchange with removal of infected components, insertion of an interim antibiotic eluting cement spacer and re-implantation of an extensively coated uncemented prosthesis on the femoral side. Systemic antibiotic treatment following each stage consisted of an abridged course of 5 days post-operative intra-venous administration followed by complete cessation of anti-microbial therapy.
    At a mean follow-up of 35 months (minimum 24 months), there were no cases of recurrent prosthetic infection and no patient had required revision for aseptic loosening or mechanical instability on the femoral side. The combination of effective-staged surgical joint debridement, a shortened post-operative course of systemic antibiotic treatment and an adequate latent period before re-implantation has led to encourage early results in this series of revised chronic hip joint prosthetic infections.
    Item Type
    Article
    Language
    en
    ISSN
    1434-3916
    ae974a485f413a2113503eed53cd6c53
    10.1007/s00402-008-0683-x
    Scopus Count
    Collections
    University Hospitals Limerick

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