• Avascular necrosis of bilateral femoral heads in a patient with Fabry's disease.

      O'Neill, Francis; Rice, John; Trauma and Orthopaedic Department, Kerry General Hospital, Tralee, Kerry, Ireland. fneill@hotmail.com (2012-07-13)
      The underlying cause of avascular necrosis (AVN) of the femoral head is often not apparent. We report the case of a 26 year old builder with a four month history of bilateral hip pain, and a diagnosis of bilateral femoral head avascular necrosis. Fabry's disease was identified as the probable cause. Since 2001, enzyme replacement therapy for Fabry's disease has become available, with a potential to influence the disease process, and this is of potential importance to clinicians treating AVN.