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dc.contributor.authorCoffey, John Calvin
dc.contributor.authorMcCarthy, Eoghan
dc.contributor.authorKavanagh, Eamon
dc.contributor.authorRedmond, Henry Paul
dc.contributor.authorKirwan, William Oliver
dc.date.accessioned2012-01-10T13:03:25Z
dc.date.available2012-01-10T13:03:25Z
dc.date.issued2009-01
dc.identifier.citationPouchitis: an evolving clinical enigma--a review. 2009, 52 (1):140-53 Dis. Colon Rectumen
dc.identifier.issn1530-0358
dc.identifier.pmid19273970
dc.identifier.doi10.1007/DCR.0b013e31819739d6
dc.identifier.urihttp://hdl.handle.net/10147/201290
dc.descriptionWhile the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.en
dc.description.abstractWhile the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshColonic Pouches
dc.subject.meshHumans
dc.subject.meshPouchitis
dc.subject.meshRisk Factors
dc.titlePouchitis: an evolving clinical enigma--a review.en
dc.typeArticleen
dc.contributor.departmentDepartment of Academic Surgery, Cork University Hospital, Cork, Ireland. calvincoffey@hotmail.comen
dc.identifier.journalDiseases of the colon and rectumen
dc.description.provinceMunster
html.description.abstractWhile the overall incidence of pouchitis is low, extensive research continues at clinical and experimental levels in attempts to unravel its etiology. The ileal pouch and pouchitis together represent a unique in vivo opportunity to study mucosal adaptation and inflammation in depth. In the recent past, molecular data relating to pouchitis has significantly expanded. These data provide invaluable insight into intracellular and extracellular events that underpin mucosal adaptation and inflammation. Advances in classification, risk factor evaluation, and prevention have meant that a review of this data, as well as its relationship to our current understanding of pouchitis, is both timely and warranted. Therefore, the aim of this review is to summarize recent data in the context of the established literature.


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