Evaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study.
AffiliationDepartment of Anaesthesia and Intensive Care Medicine, St Vincent's University Hospital, Dublin 4, Ireland.
Blood Gas Analysis
MetadataShow full item record
CitationEvaluation of a blood conservation strategy in the intensive care unit: a prospective, randomised study. 2009, 20 (2):219-23 Middle East J Anesthesiol
JournalMiddle East journal of anesthesiology
AbstractAnemia is a common problem in the ICU population. Most patients are anemic at admission, their hemoglobin concentrations declining further thereafter. The aim of the present study was to evaluate the effect of a combination strategy, involving closed arterial blood gas sampling and the use of pediatric vials for phlebotomy (Group A), on the sampling-induced blood loss and the rate of decline in hemoglobin in adult ICU patients. Combination (Group A) was compared to the current standard technique of arterial line sampling and adult vial phlebotomy (Group B) in a prospective, randomised, ethically-approved trial for the first 72 hours of their ICU stay. Peri-operative, oncology, coagulopathic and uremic patients were excluded. All other ICU patients with arterial cannulae and predicted to stay beyond 3 days, were enrolled.
39 patients entered the study, 20 in Group A, and 19 in Group B. Data collection was complete for all. There was a statistically significant difference in sampling-induced blood loss between the groups over the first 72 hours of treatment (mean +/- standard deviation: 15.16 +/- 5.3 ml Group A vs 45.11 +/- 14 ml Group B, p<0.001). There was a smaller decline in mean hemoglobin level, which was not statistically significant (0.79 +/- 0.6 g/dL vs 1.30 +/- 1.13, p = 0.09).
Overall, this strategy reduced measurable blood losses from phlebotomy. In larger trials it might also preserve hemoglobin levels.
- Anemia, transfusion, and phlebotomy practices in critically ill patients with prolonged ICU length of stay: a cohort study.
- Authors: Chant C, Wilson G, Friedrich JO
- Issue date: 2006
- A clinical evaluation of a blood conservation device in medical intensive care unit patients.
- Authors: Peruzzi WT, Parker MA, Lichtenthal PR, Cochran-Zull C, Toth B, Blake M
- Issue date: 1993 Apr
- Identifying factors to minimize phlebotomy-induced blood loss in the pediatric intensive care unit.
- Authors: Valentine SL, Bateman ST
- Issue date: 2012 Jan
- Anemia and blood transfusion in trauma patients admitted to the intensive care unit.
- Authors: Shapiro MJ, Gettinger A, Corwin HL, Napolitano L, Levy M, Abraham E, Fink MP, MacIntyre N, Pearl RG, Shabot MM
- Issue date: 2003 Aug
- The CRIT Study: Anemia and blood transfusion in the critically ill--current clinical practice in the United States.
- Authors: Corwin HL, Gettinger A, Pearl RG, Fink MP, Levy MM, Abraham E, MacIntyre NR, Shabot MM, Duh MS, Shapiro MJ
- Issue date: 2004 Jan