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dc.contributor.authorO'Regan, Kevin
dc.contributor.authorO'Mahony, Edward
dc.contributor.authorMacEneaney, Peter
dc.contributor.authorFitzgerald, Edward
dc.contributor.authorMaher, Michael M
dc.date.accessioned2012-01-09T15:51:10Z
dc.date.available2012-01-09T15:51:10Z
dc.date.issued2009-10
dc.identifier.citationFulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia. 2009, 39 (10):1095-7 Pediatr Radiolen
dc.identifier.issn1432-1998
dc.identifier.pmid19547962
dc.identifier.doi10.1007/s00247-009-1324-4
dc.identifier.urihttp://hdl.handle.net/10147/200971
dc.descriptionNecrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.en
dc.description.abstractNecrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.
dc.language.isoenen
dc.subject.meshAdolescent
dc.subject.meshFanconi Anemia
dc.subject.meshFasciitis, Necrotizing
dc.subject.meshFatal Outcome
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLeg
dc.subject.meshRetroperitoneal Space
dc.titleFulminant limb and retroperitoneal necrotizing fasciitis in a 15-year-old girl with Fanconi anaemia.en
dc.typeArticleen
dc.contributor.departmentDepartment of Radiology, Mercy University Hospital, Cork, Republic of Ireland. kevin.oregan@ucc.ieen
dc.identifier.journalPediatric radiologyen
dc.description.provinceMunster
html.description.abstractNecrotizing fasciitis (NF) is an uncommon soft-tissue infection in children that carries a high mortality rate. We present a 15-year-old girl with chronic pancytopenia secondary to Fanconi anaemia who developed extensive NF of the lower limb, which unfortunately resulted in a fatal outcome. Immunodeficiency is a known risk factor for the development of this condition. The findings in this case demonstrate that patients with Fanconi anaemia may be susceptible to NF and that the clinical course may be more aggressive due to underlying immunosuppression. Prompt diagnosis of NF is vital in order to initiate appropriate treatment and to optimize patient outcome. Radiological investigation demonstrated extensive soft-tissue gas and destruction affecting the entire lower limb, abdominal wall and retroperitoneum, which led to timely definitive diagnosis and management.


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