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dc.contributor.authorMorcos, Ashraf
dc.contributor.authorDinan, Ted
dc.contributor.authorQuigley, Eamonn M M
dc.date.accessioned2012-01-06T15:57:14Z
dc.date.available2012-01-06T15:57:14Z
dc.date.issued2009-11
dc.identifier.citationIrritable bowel syndrome: role of food in pathogenesis and management. 2009, 10 (4):237-46 J Dig Disen
dc.identifier.issn1751-2980
dc.identifier.pmid19906102
dc.identifier.doi10.1111/j.1751-2980.2009.00392.x
dc.identifier.urihttp://hdl.handle.net/10147/200778
dc.descriptionPatients with the irritable bowel syndrome (IBS) commonly report the precipitation of symptoms on food ingestion. Though the role of dietary constituents in IBS has not been extensively studied, food could contribute to symptom onset or even the causation of IBS through a number of mechanisms. First, the physiological response of the intestine to food ingestion could precipitate symptoms in predisposed individuals; second, there is some evidence that allergy or intolerance to a particular food can produce IBS-like symptoms, third, certain foods may alter the composition of the luminal milieu, either directly or indirectly through effects on bacterial metabolism, and thus induce symptoms and, finally, IBS may develop following exposure to food-borne pathogens. Anticipatory, psychological factors generated by previous negative experiences with food ingestion or other factors may also contribute though their contribution has been scarcely quantified. Not surprisingly, there is considerable interest in the potential roles of diet and food supplements in the therapy of IBS; for the most part, the evidence base for such recommendations remains slim though certain probiotics show considerable promise.en
dc.description.abstractPatients with the irritable bowel syndrome (IBS) commonly report the precipitation of symptoms on food ingestion. Though the role of dietary constituents in IBS has not been extensively studied, food could contribute to symptom onset or even the causation of IBS through a number of mechanisms. First, the physiological response of the intestine to food ingestion could precipitate symptoms in predisposed individuals; second, there is some evidence that allergy or intolerance to a particular food can produce IBS-like symptoms, third, certain foods may alter the composition of the luminal milieu, either directly or indirectly through effects on bacterial metabolism, and thus induce symptoms and, finally, IBS may develop following exposure to food-borne pathogens. Anticipatory, psychological factors generated by previous negative experiences with food ingestion or other factors may also contribute though their contribution has been scarcely quantified. Not surprisingly, there is considerable interest in the potential roles of diet and food supplements in the therapy of IBS; for the most part, the evidence base for such recommendations remains slim though certain probiotics show considerable promise.
dc.language.isoenen
dc.subject.meshDietary Supplements
dc.subject.meshEnteritis
dc.subject.meshFood
dc.subject.meshHumans
dc.subject.meshIrritable Bowel Syndrome
dc.subject.meshProbiotics
dc.titleIrritable bowel syndrome: role of food in pathogenesis and management.en
dc.typeArticleen
dc.contributor.departmentDepartment of Gastroenterology and Internal Medicine, Midwestern Regional Hospital, Limerick, Ireland.en
dc.identifier.journalJournal of digestive diseasesen
dc.description.provinceMunster
html.description.abstractPatients with the irritable bowel syndrome (IBS) commonly report the precipitation of symptoms on food ingestion. Though the role of dietary constituents in IBS has not been extensively studied, food could contribute to symptom onset or even the causation of IBS through a number of mechanisms. First, the physiological response of the intestine to food ingestion could precipitate symptoms in predisposed individuals; second, there is some evidence that allergy or intolerance to a particular food can produce IBS-like symptoms, third, certain foods may alter the composition of the luminal milieu, either directly or indirectly through effects on bacterial metabolism, and thus induce symptoms and, finally, IBS may develop following exposure to food-borne pathogens. Anticipatory, psychological factors generated by previous negative experiences with food ingestion or other factors may also contribute though their contribution has been scarcely quantified. Not surprisingly, there is considerable interest in the potential roles of diet and food supplements in the therapy of IBS; for the most part, the evidence base for such recommendations remains slim though certain probiotics show considerable promise.


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