The effect of midazolam on neutrophil mitogen-activated protein kinase.
Affiliation
Cork University Hospital, Cork, Ireland. kamrang@hotmail.comIssue Date
2010-06MeSH
Antigens, CD11bAntigens, CD18
Enzyme Inhibitors
Humans
Hypnotics and Sedatives
Imidazoles
Midazolam
Neutrophils
Pyridines
Reperfusion Injury
p38 Mitogen-Activated Protein Kinases
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The effect of midazolam on neutrophil mitogen-activated protein kinase. 2010, 27 (6):562-5 Eur J AnaesthesiolJournal
European journal of anaesthesiologyDOI
10.1097/EJA.0b013e3283328442PubMed ID
20421794Abstract
Midazolam diminishes in-vitro ischaemia-reperfusion-induced phosphorylation of p38 MAPK in neutrophils. This decrease in p38 MAPK activation results in decreased neutrophil CD11b/CD18 molecule expression.Item Type
ArticleLanguage
enISSN
1365-2346ae974a485f413a2113503eed53cd6c53
10.1097/EJA.0b013e3283328442
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