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Authors
Mertes, P MTajima, K
Regnier-Kimmoun, M A
Lambert, M
Iohom, G
Guéant-Rodriguez, R M
Malinovsky, J M
Affiliation
Service d'Anesthésie-Réanimation Chirurgicale, CHU de Nancy, Hôpital Central, 29 Avenue de Lattre de Tassigny, 54035 Nancy Cedex, France. pm.mertes@chu-nancy.frIssue Date
2010-07MeSH
Adrenergic AgonistsAnalgesics, Opioid
Anaphylaxis
Anesthesia
Anesthetics, Local
Anti-Bacterial Agents
Anti-Inflammatory Agents, Non-Steroidal
Aprotinin
Basophils
Epinephrine
Fluid Therapy
Humans
Hypnotics and Sedatives
Immunoglobulin E
Intraoperative Complications
Latex
Neuromuscular Blocking Agents
Risk Factors
Serine Proteinase Inhibitors
Skin Tests
Tryptases
Metadata
Show full item recordCitation
Perioperative anaphylaxis. 2010, 94 (4):761-89, xi Med. Clin. North Am.Publisher
ElsevierJournal
The Medical clinics of North AmericaDOI
10.1016/j.mcna.2010.04.002PubMed ID
20609862Abstract
The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.Item Type
ArticleLanguage
enISSN
1557-9859ae974a485f413a2113503eed53cd6c53
10.1016/j.mcna.2010.04.002
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