Perioperative anaphylaxis.

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Authors
Mertes, P M
Tajima, K
Regnier-Kimmoun, M A
Lambert, M
Iohom, G
Guéant-Rodriguez, R M
Malinovsky, J M
Affiliation
Service d'Anesthésie-Réanimation Chirurgicale, CHU de Nancy, Hôpital Central, 29 Avenue de Lattre de Tassigny, 54035 Nancy Cedex, France. pm.mertes@chu-nancy.fr
Issue Date
2010-07
MeSH
Adrenergic Agonists
Analgesics, Opioid
Anaphylaxis
Anesthesia
Anesthetics, Local
Anti-Bacterial Agents
Anti-Inflammatory Agents, Non-Steroidal
Aprotinin
Basophils
Epinephrine

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Citation
Perioperative anaphylaxis. 2010, 94 (4):761-89, xi Med. Clin. North Am.
Publisher
Elsevier
Journal
The Medical clinics of North America
URI
http://hdl.handle.net/10147/200263
DOI
10.1016/j.mcna.2010.04.002
PubMed ID
20609862
Abstract
The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents are most frequently incriminated, followed by latex and antibiotics, although any drug or substance used may be a culprit. Diagnosis relies on tryptase measurements at the time of the reaction and skin tests, specific immunoglobulin E, or basophil activation assays. Treatment consists of rapid volume expansion and epinephrine administration titrated to symptom severity.
Item Type
Article
Language
en
ISSN
1557-9859
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