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    Maintenance hemodialysis patients have high cumulative radiation exposure.

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    Authors
    Kinsella, Sinead M
    Coyle, Joe P
    Long, Eva B
    McWilliams, Sebastian R
    Maher, Michael M
    Clarkson, Michael R
    Eustace, Joseph A
    Affiliation
    Department of Nephrology, Cork University Hospital, Wilton, Cork, Ireland.
    Issue Date
    2010-10
    MeSH
    Adult
    Aged
    Female
    Humans
    Kidney Failure, Chronic
    Male
    Middle Aged
    Radiation Dosage
    Radiation, Ionizing
    Radiography
    Retrospective Studies
    Risk Assessment
    Risk Factors
    Tomography, X-Ray Computed
    Treatment Outcome
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    Citation
    Maintenance hemodialysis patients have high cumulative radiation exposure. 2010, 78 (8):789-93 Kidney Int.
    Journal
    Kidney international
    URI
    http://hdl.handle.net/10147/200253
    DOI
    10.1038/ki.2010.196
    PubMed ID
    20592715
    Abstract
    Hemodialysis is associated with an increased risk of neoplasms which may result, at least in part, from exposure to ionizing radiation associated with frequent radiographic procedures. In order to estimate the average radiation exposure of those on hemodialysis, we conducted a retrospective study of 100 patients in a university-based dialysis unit followed for a median of 3.4 years. The number and type of radiological procedures were obtained from a central radiology database, and the cumulative effective radiation dose was calculated using standardized, procedure-specific radiation levels. The median annual radiation dose was 6.9 millisieverts (mSv) per patient-year. However, 14 patients had an annual cumulative effective radiation dose over 20 mSv, the upper averaged annual limit for occupational exposure. The median total cumulative effective radiation dose per patient over the study period was 21.7 mSv, in which 13 patients had a total cumulative effective radiation dose over 75 mSv, a value reported to be associated with a 7% increased risk of cancer-related mortality. Two-thirds of the total cumulative effective radiation dose was due to CT scanning. The average radiation exposure was significantly associated with the cause of end-stage renal disease, history of ischemic heart disease, transplant waitlist status, number of in-patient hospital days over follow-up, and death during the study period. These results highlight the substantial exposure to ionizing radiation in hemodialysis patients.
    Item Type
    Article
    Language
    en
    ISSN
    1523-1755
    ae974a485f413a2113503eed53cd6c53
    10.1038/ki.2010.196
    Scopus Count
    Collections
    Cork University Hospital

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