Cumulative ionizing radiation exposure in patients with end stage kidney disease: a 6-year retrospective analysis.
Authors
Coyle, JoeKinsella, Sinead
McCarthy, Siobhain
Macwilliams, Sebastian
McLaughlin, Patrick
Eustace, Joseph
Maher, Michael M
Affiliation
Radiology Department, Cork University Hospital, Wilton, Cork, Ireland, joecoyle1@gmail.com.Issue Date
2011-08-13
Metadata
Show full item recordCitation
Cumulative ionizing radiation exposure in patients with end stage kidney disease: a 6-year retrospective analysis. 2011: Abdom ImagingPublisher
SpringerJournal
Abdominal imagingDOI
10.1007/s00261-011-9786-xPubMed ID
21842156Abstract
OBJECTIVE: To quantify cumulative exposure to ionizing radiation in patients with end stage kidney disease (ESKD). To investigate factors which may be independently associated with risk of high cumulative effective dose (CED). MATERIALS AND METHODS: The study had local institutional review board ethical approval. We conducted a retrospective study of 394 period prevalent ESKD patients attending a single tertiary referral centre between 2004 and 2009. Patient demographics were obtained from case records. Details of radiological investigations were obtained from the institutional radiology computerized database. CED was calculated using standard procedure specific radiation levels. High exposure was defined as CED > 50 mSv, an exposure which has been reported to increase cancer mortality by 5%. Data were compared using Pearson χ(2) and Mann-Whitney U test or Kruskal-Wallis tests. RESULTS: 394 patients were followed for a median of 4 years (1518 patient years follow-up). Of these 63% were male. Seventeen percent of patients had a CED of >50 mSv. Computed tomography (CT) accounted for 9% of total radiological studies/procedures while contributing 61.4% of total study dose. Median cumulative dose and median dose per patient year were significantly higher in the hemodialysis (HD) group (15.13 and 5.79 mSv, respectively) compared to the post-transplant group (2.9 and 0.52 mSv, respectively) (P < 0.001). CONCLUSION: ESKD patients are at risk of cumulative exposure to significant levels of diagnostic radiation. The majority of this exposure is imparted as a result of CT examinations to patients in the HD group.Item Type
ArticleLanguage
enISSN
1432-0509ae974a485f413a2113503eed53cd6c53
10.1007/s00261-011-9786-x
Scopus Count
Collections
Related articles
- Maintenance hemodialysis patients have high cumulative radiation exposure.
- Authors: Kinsella SM, Coyle JP, Long EB, McWilliams SR, Maher MM, Clarkson MR, Eustace JA
- Issue date: 2010 Oct
- Radiation exposure from medical imaging in dialyzed patients undergoing renal pre-transplant evaluation.
- Authors: De Mauri A, Matheoud R, Carriero A, Lizio D, Chiarinotti D, Brambilla M
- Issue date: 2017 Feb
- Cumulative radiation dose from medical imaging in kidney transplant patients.
- Authors: De Mauri A, Brambilla M, Izzo C, Matheoud R, Chiarinotti D, Carriero A, Stratta P, De Leo M
- Issue date: 2012 Sep
- Cumulative radiation exposure during follow-up after curative surgery for gastric cancer.
- Authors: Lee YJ, Chung YE, Lim JS, Kim JH, Kim YJ, Lee HJ, You JS, Kim MJ, Kim KW
- Issue date: 2012 Mar-Apr
- Radiation dose from medical imaging in end stage renal disease patients: a Nationwide Italian Survey.
- Authors: Postorino M, Lizio D, De Mauri A, Marino C, Tripepi GL, Zoccali C, Brambilla M, MIRA-ESRD Study Investigators
- Issue date: 2021 Jun