• Login
    View Item 
    •   Home
    • Hospital Research
    • Munster
    • Cork University Hospital
    • View Item
    •   Home
    • Hospital Research
    • Munster
    • Cork University Hospital
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Map of Submissions

    Home Page
    UlsterN
    4378
    UlsterS
    4378
    Connacht
    1408
    Munster
    62
    Leinster
    426

    Browse

    All of Lenus, The Irish Health RepositoryCommunitiesTitleAuthorsDate publishedSubjectsThis CollectionTitleAuthorsDate publishedSubjects

    My Account

    LoginRegister

    About

    About LenusDirectory of Open Access JournalsOpen Access Publishing GuideHSE Library Guide to Publishers' PoliciesFAQsTerms and ConditionsVision StatementORCID Unique identifiers for ResearchersHSE position statement on Open AccessNational Open Research Forum (NORF)Zenodo (European Open Research repository)

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Oxidative and inflammatory status in Type 2 diabetes patients with periodontitis.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Allen, Edith M
    Matthews, John B
    O' Halloran, Domhnall J
    Griffiths, Helen R
    Chapple, Iain L
    Affiliation
    Department of Restorative Dentistry, Cork University Dental School and Hospital, Wilton, Ireland. e.allen@ucc.ie
    Issue Date
    2011-10
    
    Metadata
    Show full item record
    Citation
    Oxidative and inflammatory status in Type 2 diabetes patients with periodontitis. 2011, 38 (10):894-901 J. Clin. Periodontol.
    Journal
    Journal of clinical periodontology
    URI
    http://hdl.handle.net/10147/197853
    DOI
    10.1111/j.1600-051X.2011.01764.x
    PubMed ID
    21883360
    Abstract
    To determine the impact of periodontitis on oxidative/inflammatory status and diabetes control in Type 2 diabetes.
    A comparative study of 20 Type 2 diabetes patients with periodontitis [body mass index (BMI) 31+5], 20-age/gender-matched, non-periodontitis Type 2 diabetes controls (BMI 29+6) and 20 non-diabetes periodontitis controls (BMI 25+4) had periodontal examinations and fasting blood samples collected. Oxidative stress was determined by plasma small molecule antioxidant capacity (pSMAC) and protein carbonyl levels; inflammatory status by total/differential leucocytes, fibrinogen and high sensitivity C-reactive protein (hsCRP); diabetes status by fasting glucose, HbA1c, lipid profile, insulin resistance and secretion. Statistical analysis was performed using SPSS.
    pSMAC was lower (p=0.03) and protein carbonyls higher (p=0.007) in Type 2 diabetes patients with periodontitis compared with those without periodontitis. Periodontitis was associated with significantly higher HbA1c (p=0.002) and fasting glucose levels (p=0.04) and with lower β-cell function (HOMA-β; p=0.01) in diabetes patients. Periodontitis had little effect on inflammatory markers or lipid profiles, but Type 2 diabetes patients with periodontitis had higher levels of hsCRP than those without diabetes (p=0.004) and the lowest levels of HDL-cholesterol of all groups.
    Periodontitis is associated with increased oxidative stress and compromised glycaemic control in Type 2 diabetes patients.
    Item Type
    Article
    Language
    en
    ISSN
    1600-051X
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1600-051X.2011.01764.x
    Scopus Count
    Collections
    Cork University Hospital

    entitlement

    Related articles

    • Association of periodontal parameters with metabolic level and systemic inflammatory markers in patients with type 2 diabetes.
    • Authors: Chen L, Wei B, Li J, Liu F, Xuan D, Xie B, Zhang J
    • Issue date: 2010 Mar
    • Inflammatory cytokines, adiponectin, insulin resistance and metabolic control after periodontal intervention in patients with type 2 diabetes and chronic periodontitis.
    • Authors: Sun WL, Chen LL, Zhang SZ, Wu YM, Ren YZ, Qin GM
    • Issue date: 2011
    • Effects of non-surgical periodontal treatment on clinical response, serum inflammatory parameters, and metabolic control in patients with type 2 diabetes: a randomized study.
    • Authors: Chen L, Luo G, Xuan D, Wei B, Liu F, Li J, Zhang J
    • Issue date: 2012 Apr
    • Association of periodontal disease with glycemic control in patients with type 2 diabetes in Indian population.
    • Authors: Khanuja PK, Narula SC, Rajput R, Sharma RK, Tewari S
    • Issue date: 2017 Mar
    • Adipokines and inflammatory mediators after initial periodontal treatment in patients with type 2 diabetes and chronic periodontitis.
    • Authors: Kardeşler L, Buduneli N, Cetinkalp S, Kinane DF
    • Issue date: 2010 Jan
    HSE Library | Health Service Executive | Dr Steevens’ Hospital, Dublin 8 | Republic of Ireland | Eircode: D08 W2A8
    lenus@hse.ie
    DSpace software copyright © 2002-2017  DuraSpace
    Contact Us | Disclaimer
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.