Pneumococcal meningitis: clinical outcomes in a pre-vaccine era at a Dublin paediatric hospital, 1999-2007.
Affiliation
Department of Paediatrics, Children's University Hospital, Temple Street, Dublin 1, Ireland. Juliette.Lucey@health.wa.gov.auIssue Date
2011-03MeSH
AdolescentChild
Child, Preschool
Female
Hospitals, Pediatric
Humans
Incidence
Infant
Infant, Newborn
Ireland
Length of Stay
Male
Meningitis, Pneumococcal
Retrospective Studies
Serotyping
Metadata
Show full item recordCitation
Pneumococcal meningitis: clinical outcomes in a pre-vaccine era at a Dublin paediatric hospital, 1999-2007. 2011, 180 (1):47-50 Ir J Med SciJournal
Irish journal of medical scienceDOI
10.1007/s11845-010-0620-1PubMed ID
21072618Abstract
To document the long-term outcomes of pneumococcal meningitis in children presenting to a Dublin paediatric hospital in the pre-pneumococcal conjugate vaccine (PCV7) era (1998-2007).Subjects with pneumococcal meningitis were identified at The Children's University Hospital, Dublin through the hospital surveillance system and laboratory archives.
44 children were identified with S. pneumoniae meningitis. Mean age of presentation was 23.45 months (2 days to 13 years) and 28 (65%) cases were less than 12 months old. Eight (18.6%) children died. 55% of cases were left with significant deficits. Of the survivors, 7 (20%) had moderate to severe neurological sequelae.
Pneumococcal meningitis is a devastating childhood disease with significant mortality and morbidity, especially in those less than 2 years of age. These data provide a baseline against which the impact of PCV7 on pneumococcal meningitis can be measured.
Item Type
ArticleLanguage
enISSN
1863-4362ae974a485f413a2113503eed53cd6c53
10.1007/s11845-010-0620-1