Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland.
AffiliationAcademic Department of Obstetrics & Gynaecology, Coombe Women and Infants University Hospital & Trinity College Dublin, Dublin 8, Republic of Ireland.
Fetal Alcohol Syndrome
MetadataShow full item record
CitationPrevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland. 2011, 11:27 BMC Pregnancy Childbirth
JournalBMC pregnancy and childbirth
AbstractEvidence-based advice on alcohol consumption is required for pregnant women and women planning a pregnancy. Our aim was to investigate the prevalence, predictors and perinatal outcomes associated with peri-conceptional alcohol consumption.
A cohort study of 61,241 women who booked for antenatal care and delivered in a large urban maternity hospital between 2000 and 2007. Self-reported alcohol consumption at the booking visit was categorised as low (0-5 units per week), moderate (6-20 units per week) and high (>20 units per week).
Of the 81% of women who reported alcohol consumption during the peri-conceptional period, 71% reported low intake, 9.9% moderate intake and 0.2% high intake. Factors associated with moderate alcohol consumption included being in employment OR 4.47 (95% CI 4.17 to 4.80), Irish nationality OR 16.5 (95% CI 14.9 to 18.3), private health care OR 5.83 (95% CI 5.38 to 6.31) and smoking OR 1.86 (95% CI 1.73 to 2.01). Factors associated with high consumption included maternal age less than 25 years OR 2.70 (95% CI 1.86 to 3.91) and illicit drug use OR 6.46 (95% CI 3.32 to 12.60). High consumption was associated with very preterm birth (<32 weeks gestation) even after controlling for socio-demographic factors, adjusted OR 3.15 (95% CI 1.26-7.88). Only three cases of Fetal Alcohol Syndrome were recorded (0.05 per 1000 total births), one each in the low, moderate and high consumption groups.
Public Health campaigns need to emphasise the importance of peri-conceptional health and pre-pregnancy planning. Fetal Alcohol Syndrome is likely to be under-reported despite the high prevalence of alcohol consumption in this population.
- Behavioural change in relation to alcohol exposure in early pregnancy and impact on perinatal outcomes--a prospective cohort study.
- Authors: Murphy DJ, Mullally A, Cleary BJ, Fahey T, Barry J
- Issue date: 2013 Jan 16
- The effects of maternal alcohol consumption during pregnancy on adverse fetal outcomes among pregnant women attending antenatal care at public health facilities in Gondar town, Northwest Ethiopia: a prospective cohort study.
- Authors: Addila AE, Azale T, Gete YK, Yitayal M
- Issue date: 2021 Aug 26
- A prospective cohort study of alcohol exposure in early and late pregnancy within an urban population in Ireland.
- Authors: Murphy DJ, Dunney C, Mullally A, Adnan N, Fahey T, Barry J
- Issue date: 2014 Feb 17
- Alcohol Intake in Early Pregnancy and Spontaneous Preterm Birth: A Cohort Study.
- Authors: Weile LKK, Hegaard HK, Wu C, Tabor A, Wolf HT, Kesmodel US, Henriksen TB, Nohr EA
- Issue date: 2020 Feb
- Fetal growth and maternal alcohol consumption during early pregnancy.
- Authors: Reynolds CME, Egan B, O'Malley EG, McMahon L, Sheehan SR, Turner MJ
- Issue date: 2019 May