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    Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland.

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    Authors
    Mullally, Aoife
    Cleary, Brian J
    Barry, Joe
    Fahey, Tom P
    Murphy, Deirdre J
    Affiliation
    Academic Department of Obstetrics & Gynaecology, Coombe Women and Infants University Hospital & Trinity College Dublin, Dublin 8, Republic of Ireland.
    Issue Date
    2011-04
    MeSH
    Adult
    Age Factors
    Alcohol Drinking
    Cohort Studies
    Female
    Fertilization
    Fetal Alcohol Syndrome
    Humans
    Ireland
    Pregnancy
    Premature Birth
    Retrospective Studies
    Risk Factors
    Self Report
    Socioeconomic Factors
    Substance-Related Disorders
    Urban Population
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    Citation
    Prevalence, predictors and perinatal outcomes of peri-conceptional alcohol exposure--retrospective cohort study in an urban obstetric population in Ireland. 2011, 11:27 BMC Pregnancy Childbirth
    Journal
    BMC pregnancy and childbirth
    URI
    http://hdl.handle.net/10147/141056
    DOI
    10.1186/1471-2393-11-27
    PubMed ID
    21481224
    Abstract
    Evidence-based advice on alcohol consumption is required for pregnant women and women planning a pregnancy. Our aim was to investigate the prevalence, predictors and perinatal outcomes associated with peri-conceptional alcohol consumption.
    A cohort study of 61,241 women who booked for antenatal care and delivered in a large urban maternity hospital between 2000 and 2007. Self-reported alcohol consumption at the booking visit was categorised as low (0-5 units per week), moderate (6-20 units per week) and high (>20 units per week).
    Of the 81% of women who reported alcohol consumption during the peri-conceptional period, 71% reported low intake, 9.9% moderate intake and 0.2% high intake. Factors associated with moderate alcohol consumption included being in employment OR 4.47 (95% CI 4.17 to 4.80), Irish nationality OR 16.5 (95% CI 14.9 to 18.3), private health care OR 5.83 (95% CI 5.38 to 6.31) and smoking OR 1.86 (95% CI 1.73 to 2.01). Factors associated with high consumption included maternal age less than 25 years OR 2.70 (95% CI 1.86 to 3.91) and illicit drug use OR 6.46 (95% CI 3.32 to 12.60). High consumption was associated with very preterm birth (<32 weeks gestation) even after controlling for socio-demographic factors, adjusted OR 3.15 (95% CI 1.26-7.88). Only three cases of Fetal Alcohol Syndrome were recorded (0.05 per 1000 total births), one each in the low, moderate and high consumption groups.
    Public Health campaigns need to emphasise the importance of peri-conceptional health and pre-pregnancy planning. Fetal Alcohol Syndrome is likely to be under-reported despite the high prevalence of alcohol consumption in this population.
    Item Type
    Article
    Language
    en
    ISSN
    1471-2393
    ae974a485f413a2113503eed53cd6c53
    10.1186/1471-2393-11-27
    Scopus Count
    Collections
    Coombe Women & Infants University Hospital

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