An imbalance in progenitor cell populations reflects tumour progression in breast cancer primary culture models.
Cottell, David C
Shelly, Martin J
Dervan, Peter A
Kell, Malcolm R
Hill, Arnold D K
Hopkins, Ann M
AffiliationDepartment of Surgery, Royal College of Surgeons in Ireland; Dublin, Ireland.
Cell Culture Techniques
Keratins, Type I
Neoplastic Stem Cells
Tumor Cells, Cultured
Tumor Markers, Biological
MetadataShow full item record
CitationAn imbalance in progenitor cell populations reflects tumour progression in breast cancer primary culture models. 2011, 30:45 J. Exp. Clin. Cancer Res.
JournalJournal of experimental & clinical cancer research : CR
AbstractOur results suggest that an imbalance in tumour progenitor subpopulations imbalances the functional relationship between proliferation and senescence, creating a microenvironment favouring tumour progression.
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