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    SubjectsANTIBIOTICS (1)CASE STUDY (1)COMMUNITY HEALTH (1)COUNSELLING (1)DIAGNOSIS (1)View MoreJournal
    Irish Medical Journal (5)
    AuthorsBradley, C. (1)Clair, J (1)Collins, J (1)Cotter, O (1)Curran, D (1)View MoreYear (Issue Date)2013 (1)2016 (1)2017 (1)2018 (1)2019 (1)TypesArticle (5)

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    The Intensity of QuantiFERON TB-Gold Response does not Differentiate Active from Latent Tuberculosis

    F Khan, F; Cotter, O; Kennedy, B; Clair, J; O’Connor, B; Collins, J; Curran, D; O’Connor, T (Irish Medical Journal (IMJ), 2013-12)
    We analyzed positive QuantiFERON (QFT) assays, performed between July 2009 and April 2011 in the Mercy University Hospital, Cork, Ireland, which included, 94 patients with latent tuberculosis (LTBI) and 35 patients with active tuberculosis. There was no difference in the intensity of response between patients with LTBI and active tuberculosis (p=0.1589). In patients with LTBI, there were no correlations between age (p=0.353), sex (p=0.476), smoking (p=0.323), contact (p=0.612), Mantoux response (p=0.055), Irish nationality (p=0.768), previous BCG vaccination (p=0.504), WCC (p=0.187), lymphocyte count (p=0.786), neutrophil count (p=0.157) and the intensity of QFT response. Similarly in patients with active TB, there were no correlations between these variables and QFT response. The intensity of QFT response does not help to differentiate active from LTBI. The intensity of QFT response is not influenced by age, sex, smoking, remoteness of contact history, Mantoux response, nationality, CXR abnormalities, BCG vaccination and peripheral lymphocyte count.
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    Counselling in Primary Care – A General Practitioner’s Perspective

    Rafferty, M.; Bradley, C. (Irish Medical Journal, 2019-02)
    Counselling in Primary care (CIPC) is a new service introduced by the HSE in 2013, providing short-term counselling for medical-card holders, suffering from mild to moderate mental health problems.
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    Management of patients with subclinical hypothyroidism in primary

    McCarthy, E; Russell, A; Kearney, PM (Irish Medical Journal, 2016-01)
    Subclinical hypothyroidism (SCH) is defined as a raised serum thyroid stimulating hormone level with normal thyroxine. Despite a prevalence of up to 9% of the adult population there is widespread uncertainty on how to manage it. The aim of this study was to assess how older adults with SCH are managed in primary care. A retrospective case-note review was carried out on patients attending Mallow Primary Healthcare Centre. This study identified patients 65 years and over meeting the criteria for SCH in one year. The prevalence of SCH in this study was calculated as 2.9%. 22.2% of patients were treated with thyroxine. 6.1% of untreated patients progressed to clinical hypothyroidism within the study period while 18.2% spontaneously reverted to normal TSH levels.
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    An audit of empiric antibiotic choice in the inpatient management of community-acquired pneumonia

    Delaney, F; Jackson, A (Irish Medical Journal, 2017-04)
    Adherence to antimicrobial guidelines for empiric antibiotic prescribing in community-acquired pneumonia (CAP) has been reported to be worryingly low. We conducted a review of empiric antibiotic prescribing for sixty consecutive adult patients admitted to the Mercy University Hospital with a diagnosis of CAP. When analysed against local antimicrobial guidelines, guideline concordant empiric antibiotics were given in only 48% of cases, lower than the average rate in comparable studies. Concordance was 100% in cases where the CURB-65 pneumonia severity assessment score, on which the guidelines are based, was documented in the medical notes. The use of excessively broad spectrum and inappropriate antibiotics is a notable problem. This study supports the theory that lack of knowledge regarding pneumonia severity assessment tools and unfamiliarity with therapeutic guidelines are key barriers to guideline adherence, which remains a significant problem despite increased focus on antimicrobial stewardship programs in Ireland
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    Giant Cell Arteritis Presenting as an Ischaemic Upper Limb

    Fitzgerald, Gerald; O’Connor, Mortimer B.; Phelan, Mark J. (Irish Medical Journal, 2018-07)
    Aim: To present an interesting case of giant cell arteritis presenting as ischaemic upper limb. Methods Data was collected from the patient’s chart and from radiology and laboratory systems in our institution. Results: The patient had a temporal artery biopsy confirming the diagnosis of temporal arteritis. This was successfully treated with high dose steroids leading to resolution of symptoms in the arm. Conclusion: Arteritis is an important consideration to consider in patients who present with limb ischaemia as it is a reversible cause which can be treated effectively.
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