• Randomised controlled trial examining the effect of exercise in people with rheumatoid arthritis taking anti-TNFα therapy medication.

      Reid, Angela; Brady, Audrey; Blake, Catherine; Mongey, Anne-Barbara; Veale, Douglas J; FitzGerald, Oliver; Cusack, Tara; Physiotherapy Department, Our Lady's Hospice and Care Services, Harold's Cross, Dublin, Ireland. angelatreid@hotmail.com (2011)
      Substantial progress has been made in the medical management of rheumatoid arthritis (RA) over the past decade with the introduction of biologic therapies, including anti-tumour necrosis factor alpha (anti-TNFα) therapy medications. However, individuals with RA taking anti-TNFα medication continue to experience physical, psychological and functional consequences, which could potentially benefit from rehabilitation. There is evidence that therapeutic exercise should be included as an intervention for people with RA, but to date there is little evidence of the benefits of therapeutic exercise for people with RA on anti-TNFα therapy medication. A protocol for a multicentre randomised controlled three-armed study which aims to examine the effect of dynamic group exercise therapy on land or in water for people with RA taking anti-TNFα therapy medication is described.