Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction.

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Authors
O'Connell, K
Boo, T W
Keady, D
Niriain, U
O'Donovan, D
Commane, M
Faherty, C
Cormican, M
Affiliation
Department of Clinical Microbiology, University College Hospital, Galway, Ireland. karinaoconnell@gmail.com
Issue Date
2011-04
MeSH
Antibodies, Monoclonal
Antiviral Agents
Cross Infection
DNA, Viral
Disease Outbreaks
Female
Genotype
Humans
Infant
Infant, Newborn

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Citation
Use of palivizumab and infection control measures to control an outbreak of respiratory syncytial virus in a neonatal intensive care unit confirmed by real-time polymerase chain reaction. 2011, 77 (4):338-42 J. Hosp. Infect.
Journal
The Journal of hospital infection
URI
http://hdl.handle.net/10147/136381
DOI
10.1016/j.jhin.2010.12.012
PubMed ID
21330007
Additional Links
http://www.ncbi.nlm.nih.gov/pubmed/21330007
Abstract
Respiratory syncytial virus (RSV) is a potentially life-threatening infection in premature infants. We report an outbreak involving four infants in the neonatal intensive care unit (NICU) of our hospital that occurred in February 2010. RSV A infection was confirmed by real-time polymerase chain reaction. Palivizumab was administered to all infants in the NICU. There were no additional symptomatic cases and repeat RSV surveillance confirmed that there was no further cross-transmission within the unit. The outbreak highlighted the infection control challenge of very high bed occupancy in the unit and the usefulness of molecular methods in facilitating detection and management.
Item Type
Article
Language
en
ISSN
1532-2939
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