Preadipocyte factor-1 is associated with metabolic profile in severe obesity.
Affiliation
Department of Endocrinology, St Vincent's University Hospital, Elm Park, Dublin 4, Ireland. jeanoco@gmail.comIssue Date
2011-04MeSH
AdipocytesAdult
Bariatric Surgery
Case-Control Studies
Cell Count
Cell Size
Cross-Sectional Studies
Female
Health
Humans
Inflammation Mediators
Intercellular Signaling Peptides and Proteins
Macrophages
Male
Membrane Proteins
Metabolome
Middle Aged
Obesity, Morbid
Severity of Illness Index
Young Adult
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Show full item recordCitation
Preadipocyte factor-1 is associated with metabolic profile in severe obesity. 2011, 96 (4):E680-4 J. Clin. Endocrinol. Metab.Journal
The Journal of clinical endocrinology and metabolismDOI
10.1210/jc.2010-2026PubMed ID
21252254Additional Links
http://www.ncbi.nlm.nih.gov/pubmed/21252254Abstract
Adipose tissue in MHO individuals had lower levels of Pref-1, a known inhibitor of preadipocyte differentiation, and a more favorable inflammatory profile. These factors may be key to protecting this subgroup of obese individuals from the adverse metabolic profile associated with excess adiposity.Item Type
ArticleLanguage
enISSN
1945-7197ae974a485f413a2113503eed53cd6c53
10.1210/jc.2010-2026
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