• Login
    View Item 
    •   Home
    • Hospital Research
    • Leinster
    • Tallaght University Hospital
    • View Item
    •   Home
    • Hospital Research
    • Leinster
    • Tallaght University Hospital
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Map of Submissions

    Home Page
    UlsterN
    4708
    UlsterS
    4708
    Connacht
    1606
    Munster
    48
    Leinster
    426

    Browse

    All of Lenus, The Irish Health RepositoryCommunitiesTitleAuthorsDate publishedSubjectsThis CollectionTitleAuthorsDate publishedSubjects

    My Account

    LoginRegister

    About

    About LenusDirectory of Open Access JournalsOpen Access Publishing GuideNational Health Library & Knowledge ServiceGuide to Publishers' PoliciesFAQsTerms and ConditionsVision StatementRIAN Pathways to Irish ResearchHSE position statement on Open AccessNational Open Research Forum (NORF)Zenodo (European Open Research repository)

    Statistics

    Display statistics

    Trends in co-prescribing of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in Ireland.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Wan Md Adnan, Wan A H
    Zaharan, Nur L
    Bennett, Kathleen
    Wall, Catherine A
    Affiliation
    Department of Renal Medicine, Adelaide & Meath Hospital Incorporating National Children Hospital (AMNCH), Dublin 24, Ireland. wahafiz@um.edu.my
    Issue Date
    2011-03
    MeSH
    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Angiotensin Receptor Antagonists
    Angiotensin-Converting Enzyme Inhibitors
    Clinical Trials as Topic
    Diabetes Mellitus
    Drug Therapy, Combination
    Female
    Heart Failure
    Humans
    Hypertension
    Ireland
    Male
    Middle Aged
    Myocardial Ischemia
    Physician's Practice Patterns
    Regression Analysis
    Young Adult
    Show allShow less
    
    Metadata
    Show full item record
    Citation
    Trends in co-prescribing of angiotensin converting enzyme inhibitors and angiotensin receptor blockers in Ireland. 2011, 71 (3):458-66 Br J Clin Pharmacol
    Journal
    British journal of clinical pharmacology
    URI
    http://hdl.handle.net/10147/129369
    DOI
    10.1111/j.1365-2125.2010.03835.x
    PubMed ID
    21284706
    Abstract
    (i) To examine the trends in co-prescribing of angiotensin converting enzyme inhibitor (ACEI) and angiotensin-II receptor blocker (ARB) therapy and (ii) to examine the influence of major clinical trials (CALM, COOPERATE, VALIANT and ONTARGET) on co-prescribing.
    The Irish HSE-Primary Care Reimbursement Services database was used to identify patients ≥16 years old co-prescribed ACEIs and ARBs between January 2000 and April 2009 (n= 266 554 prescriptions). The rate of prescribing per 1000 general medical services (GMS) scheme population was calculated for each month. Patients with diabetes, hypertension, heart failure and ischaemic heart disease were also identified by prescribing of certain medications. A linear trend test was used to examine prescribing trends. Logistic regression was used to examine prescribing according to patient characteristics. The effects of the major trials on prescribing were examined using segmented regression analysis for 12 months pre- and post-trials.
    There was a significant linear trend in overall ACEI and ARB co-prescribing over the study period (P < 0.001). Rate of co-prescribing in January 2000 and April 2009 was 0.16 and 5.72, per 1000 eligible population, respectively. Those 45-64 years old (OR = 2.88, 95% confidence interval (CI) 2.71, 3.06) and ≥65 years (OR = 2.52, 95% CI 2.36, 2.68) were more likely to receive dual therapy compared with those <45 years old. Those with hypertension (OR = 8.85, 95% CI 8.45, 9.27), diabetes (OR = 4.10, 95% CI 3.97, 4.23) and heart failure (OR = 1.78, 95% CI 1.72, 1.84) were more likely to receive dual therapy compared with the general population. Significant increases in prescribing were observed only after the CALM (P= 0.03) and VALIANT (P= 0.007) trials.
    Increased co-prescribing of ACEIs and ARBs was observed in Ireland during 2000-09. Prescribing patterns did not appear to be affected by results from major trials.
    Item Type
    Article
    Language
    en
    ISSN
    1365-2125
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1365-2125.2010.03835.x
    Scopus Count
    Collections
    Tallaght University Hospital

    entitlement

    Related articles

    • The influence of guidelines on the use of statins: analysis of prescribing trends 1998-2002.
    • Authors: Teeling M, Bennett K, Feely J
    • Issue date: 2005 Feb
    • Pharmacotherapy Treatment Patterns, Outcomes, and Health Resource Utilization Among Patients with Heart Failure with Reduced Ejection Fraction at a U.S. Academic Medical Center.
    • Authors: Bress AP, King JB, Brixner D, Kielhorn A, Patel HK, Maya J, Lee VC, Biskupiak J, Munger M
    • Issue date: 2016 Feb
    • Combined use of renin-angiotensin-aldosterone system-acting agents: a cross-sectional study.
    • Authors: Farcas A, Leucuta D, Bucsa C, Mogosan C, Dumitrascu D
    • Issue date: 2016 Dec
    • Angiotensin receptor blockers (ARB) outperform angiotensin-converting enzyme (ACE) inhibitors on ischemic stroke prevention in patients with hypertension and diabetes - A real-world population study in Taiwan.
    • Authors: Pai PY, Muo CH, Sung FC, Ho HC, Lee YT
    • Issue date: 2016 Jul 15
    • Accepting Medication Therapy Management Recommendations to Add ACEIs or ARBs in Diabetes Care.
    • Authors: Hurwitz JT, Grizzle AJ, Augustine J, Rehfeld R, Wild A, Abraham I
    • Issue date: 2016 Jan
    National Health Library & Knowledge Service | Health Service Executive | Dr Steevens' Hospital | Dublin 8 | Ireland
    lenus@hse.ie | Tel +353 (1) 6352558
    DSpace software copyright © 2002-2017  DuraSpace
    Contact Us | Disclaimer
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.