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    Predictive factors for relapse after an integrated inpatient treatment programme for unipolar depressed and bipolar alcoholics.

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    Authors
    Farren, Conor K
    McElroy, Sharon
    Affiliation
    Department of Psychiatry, St. Patrick’s Hospital and Trinity College Dublin, James Street, Dublin 8, Ireland. cfarren@stpatsmail.com
    Issue Date
    2011-04-27T14:15:19Z
    
    Metadata
    Show full item record
    Citation
    Predictive factors for relapse after an integrated inpatient treatment programme for unipolar depressed and bipolar alcoholics., 45 (6):527-33 Alcohol Alcohol.
    Journal
    Alcohol and alcoholism (Oxford, Oxfordshire)
    URI
    http://hdl.handle.net/10147/128776
    DOI
    10.1093/alcalc/agq060
    PubMed ID
    20855410
    Additional Links
    http://alcalc.oxfordjournals.org/content/45/6/527.long
    Abstract
    The aim of this study was to examine prospectively examined predictors of relapse in alcohol dependence with comorbid affective disorder.
    One hundred and eighty-three unipolar depressed or bipolar alcoholics who completed an integrated inpatient treatment programme for dual diagnosis were assessed at baseline, post-treatment discharge and at 3 and 6 months post treatment. Backwards stepwise likelihood ratio multiple logistic regression was used to investigate the impact of multiple covariates on relapse to alcohol in the 0-3- and 3-6-month period post discharge.
    The retention rate at 3 months post discharge was 95.3% (177 patients) and at 6 months it was 87.4% (162 patients). Higher level of anxiety at baseline and discharge was significantly associated with relapse at 3, but not at 6 months, in all subjects. Higher baseline alcohol use disorder identification test scores were associated with relapse at 3 and at 6 months. Intention and planning to attend aftercare after discharge from the hospital were associated with non-relapse at 3 and 6 months, respectively. Levels of depression, of elation and of craving at baseline were not significantly predictive of relapse. Those who had relapsed at 3 months were significantly more likely to remain drinking at 6 months. Rehospitalization within the first 3 months post discharge appeared to be protective against further relapse.
    Baseline patient factors, including levels of anxiety, appear to play a significant role in relapse to alcohol in this difficult to treat population.
    Item Type
    Article
    Language
    en
    ISSN
    1464-3502
    ae974a485f413a2113503eed53cd6c53
    10.1093/alcalc/agq060
    Scopus Count
    Collections
    St. Patrick's University Hospital

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