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    The prevalence, diagnostic significance and demographic characteristics of Schneiderian first-rank symptoms in an epidemiological sample of first-episode psychoses.

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    Authors
    Ihara, Kazushige
    Morgan, Craig
    Fearon, Paul
    Dazzan, Paola
    Demjaha, Arsime
    Lloyd, Tuhina
    Kirkbride, James B
    Hayhurst, Hazel
    Murray, Robin M
    Jones, Peter B
    Affiliation
    Department of Social Medicine, Toho University School of Medicine, Tokyo, Japan.
    Issue Date
    2009
    MeSH
    Adolescent
    Adult
    Demography
    Diagnosis, Differential
    Diagnostic and Statistical Manual of Mental Disorders
    Female
    Humans
    International Classification of Diseases
    Male
    Middle Aged
    Prevalence
    Psychotic Disorders
    Schizophrenia
    Severity of Illness Index
    Young Adult
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    Citation
    The prevalence, diagnostic significance and demographic characteristics of Schneiderian first-rank symptoms in an epidemiological sample of first-episode psychoses. 2009, 42 (2):81-91 Psychopathology
    Journal
    Psychopathology
    URI
    http://hdl.handle.net/10147/128754
    DOI
    10.1159/000203340
    PubMed ID
    19225242
    Additional Links
    DOI: 10.1159/000203340
    Abstract
    The diagnostic significance of first-rank symptoms (FRSs) remains uncertain. Ethnic differences in FRSs may account for high rates of schizophrenia in minority groups. This study aims to examine the prevalence of FRSs in an epidemiological sample of first-episode psychoses stratified by relevant demographic variables. SAMPLING AND METHOD: We identified everyone aged 16-64 presenting with their first psychosis over 2 years in 3 UK centres.
    A total of 426 subjects had consensus diagnoses of DSM-IV and ICD-10 psychotic conditions. Thirty-eight percent (95% CI=33-42) reported FRSs; more frequent in those classified as having schizophrenia (DSM-IV: 55%, 95% CI=47-63; ICD-10: 51%, 95% CI=44-58) than those with affective psychoses (DSM-IV: 31%, 95% CI=22-39; ICD-10: 29%, 95% CI=21-38). FRSs in schizophrenia were more common in white British subjects, while in affective psychoses, they were more frequent in the black group. The sensitivities, specificities and positive predictive values for schizophrenia of FRSs were 55, 69 and 72% according to DSM-IV and 51, 71, 74% according to ICD-10, respectively. The sensitivities were higher in white British than in the black group.
    FRSs were common but unhelpful for differentiating schizophrenia from other psychoses as they occurred frequently in both diagnoses. Phenomenological differences did not explain the higher incidence of schizophrenia in black ethnic minority groups.
    Item Type
    Article
    Language
    en
    ISSN
    1423-033X
    ae974a485f413a2113503eed53cd6c53
    10.1159/000203340
    Scopus Count
    Collections
    St. Patrick's University Hospital

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