The prevalence, diagnostic significance and demographic characteristics of Schneiderian first-rank symptoms in an epidemiological sample of first-episode psychoses.
Authors
Ihara, KazushigeMorgan, Craig
Fearon, Paul
Dazzan, Paola
Demjaha, Arsime
Lloyd, Tuhina
Kirkbride, James B
Hayhurst, Hazel
Murray, Robin M
Jones, Peter B
Affiliation
Department of Social Medicine, Toho University School of Medicine, Tokyo, Japan.Issue Date
2009MeSH
AdolescentAdult
Demography
Diagnosis, Differential
Diagnostic and Statistical Manual of Mental Disorders
Female
Humans
International Classification of Diseases
Male
Middle Aged
Prevalence
Psychotic Disorders
Schizophrenia
Severity of Illness Index
Young Adult
Metadata
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The prevalence, diagnostic significance and demographic characteristics of Schneiderian first-rank symptoms in an epidemiological sample of first-episode psychoses. 2009, 42 (2):81-91 PsychopathologyJournal
PsychopathologyDOI
10.1159/000203340PubMed ID
19225242Additional Links
DOI: 10.1159/000203340Abstract
The diagnostic significance of first-rank symptoms (FRSs) remains uncertain. Ethnic differences in FRSs may account for high rates of schizophrenia in minority groups. This study aims to examine the prevalence of FRSs in an epidemiological sample of first-episode psychoses stratified by relevant demographic variables. SAMPLING AND METHOD: We identified everyone aged 16-64 presenting with their first psychosis over 2 years in 3 UK centres.A total of 426 subjects had consensus diagnoses of DSM-IV and ICD-10 psychotic conditions. Thirty-eight percent (95% CI=33-42) reported FRSs; more frequent in those classified as having schizophrenia (DSM-IV: 55%, 95% CI=47-63; ICD-10: 51%, 95% CI=44-58) than those with affective psychoses (DSM-IV: 31%, 95% CI=22-39; ICD-10: 29%, 95% CI=21-38). FRSs in schizophrenia were more common in white British subjects, while in affective psychoses, they were more frequent in the black group. The sensitivities, specificities and positive predictive values for schizophrenia of FRSs were 55, 69 and 72% according to DSM-IV and 51, 71, 74% according to ICD-10, respectively. The sensitivities were higher in white British than in the black group.
FRSs were common but unhelpful for differentiating schizophrenia from other psychoses as they occurred frequently in both diagnoses. Phenomenological differences did not explain the higher incidence of schizophrenia in black ethnic minority groups.
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ArticleLanguage
enISSN
1423-033Xae974a485f413a2113503eed53cd6c53
10.1159/000203340
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