• Login
    View Item 
    •   Home
    • Hospital Research
    • Leinster
    • St. Patrick's University Hospital
    • View Item
    •   Home
    • Hospital Research
    • Leinster
    • St. Patrick's University Hospital
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Map of Submissions

    Home Page
    UlsterN
    5081
    UlsterS
    5081
    Connacht
    1698
    Munster
    58
    Leinster
    466

    Browse

    All of Lenus, The Irish Health RepositoryCommunitiesTitleAuthorsDate publishedSubjectsThis CollectionTitleAuthorsDate publishedSubjects

    My Account

    LoginRegister

    About

    About LenusDirectory of Open Access JournalsOpen Access Publishing GuideNational Health Library & Knowledge ServiceGuide to Publishers' PoliciesFAQsTerms and ConditionsVision StatementORCID Unique identifiers for ResearchersHSE position statement on Open AccessNational Open Research Forum (NORF)Zenodo (European Open Research repository)

    Statistics

    Most Popular ItemsStatistics by CountryMost Popular Authors

    Differing patterns of brain structural abnormalities between black and white patients with their first episode of psychosis.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Authors
    Morgan, K D
    Dazzan, P
    Morgan, C
    Lappin, J
    Hutchinson, G
    Chitnis, X
    Suckling, J
    Fearon, P
    Jones, P B
    Leff, J
    Murray, R M
    Show allShow less
    Affiliation
    Department of Psychology, University of Westminster, London W1B 2UW, UK. k.d.morgan@wmin.ac.uk
    Issue Date
    2010-07
    MeSH
    Adult
    African Continental Ancestry Group
    Brain
    Caribbean Region
    Cerebral Ventricles
    Corpus Striatum
    European Continental Ancestry Group
    Female
    Great Britain
    Humans
    Incidence
    International Classification of Diseases
    Magnetic Resonance Imaging
    Male
    Prevalence
    Psychotic Disorders
    Substance-Related Disorders
    Show allShow less
    
    Metadata
    Show full item record
    Citation
    Differing patterns of brain structural abnormalities between black and white patients with their first episode of psychosis. 2010, 40 (7):1137-47 Psychol Med
    Journal
    Psychological medicine
    URI
    http://hdl.handle.net/10147/128751
    DOI
    10.1017/S0033291709991565
    PubMed ID
    19891807
    Additional Links
    DOI: 10.1017/S0033291709991565
    Abstract
    African-Caribbean and black African people living in the UK are reported to have a higher incidence of diagnosed psychosis compared with white British people. It has been argued that this may be a consequence of misdiagnosis. If this is true they might be less likely to show the patterns of structural brain abnormalities reported in white British patients. The aim of this study therefore was to investigate whether there are differences in the prevalence of structural brain abnormalities in white and black first-episode psychosis patients.
    We obtained dual-echo (proton density/T2-weighted) images from a sample of 75 first-episode psychosis patients and 68 healthy controls. We used high resolution magnetic resonance imaging and voxel-based methods of image analysis. Two separate analyses were conducted: (1) 34 white British patients were compared with 33 white British controls; (2) 41 African-Caribbean and black African patients were compared with 35 African-Caribbean and black African controls.
    White British patients and African-Caribbean/black African patients had ventricular enlargement and increased lenticular nucleus volume compared with their respective ethnic controls. The African-Caribbean/black African patients also showed reduced global grey matter and increased lingual gyrus grey-matter volume. The white British patients had no regional or global grey-matter loss compared with their normal ethnic counterparts but showed increased grey matter in the left superior temporal lobe and right parahippocampal gyrus.
    We found no evidence in support of our hypothesis. Indeed, the finding of reduced global grey-matter volume in the African-Caribbean/black African patients but not in the white British patients was contrary to our prediction.
    Language
    en
    ISSN
    1469-8978
    ae974a485f413a2113503eed53cd6c53
    10.1017/S0033291709991565
    Scopus Count
    Collections
    St. Patrick's University Hospital

    entitlement

    Related articles

    • Patterns of illness and care over the 5 years following onset of psychosis in different ethnic groups; the GAP-5 study.
    • Authors: Ajnakina O, Lally J, Di Forti M, Kolliakou A, Gardner-Sood P, Lopez-Morinigo J, Dazzan P, Pariante CM, Mondelli V, MacCabe J, David AS, Gaughran F, Murray RM, Vassos E
    • Issue date: 2017 Sep
    • Raised incidence rates of all psychoses among migrant groups: findings from the East London first episode psychosis study.
    • Authors: Coid JW, Kirkbride JB, Barker D, Cowden F, Stamps R, Yang M, Jones PB
    • Issue date: 2008 Nov
    • Barriers to early diagnosis of symptomatic breast cancer: a qualitative study of Black African, Black Caribbean and White British women living in the UK.
    • Authors: Jones CE, Maben J, Lucas G, Davies EA, Jack RH, Ream E
    • Issue date: 2015 Mar 13
    • Lower prevalence of pre-morbid neurological illness in African-Caribbean than White psychotic patients in England.
    • Authors: McKenzie K, Jones P, Lewis S, Williams M, Toone B, Sham P, Murray RM
    • Issue date: 2002 Oct
    • Symptom profiles and explanatory models of first-episode psychosis in African-, Caribbean- and European-origin groups in Ontario.
    • Authors: Maraj A, Anderson KK, Flora N, Ferrari M, Archie S, McKenzie KJ, ACE Project Team
    • Issue date: 2017 Apr
    Health Library Ireland | Health Service Executive | Jervis House, Jervis Street | Republic of Ireland | Eircode: D01 W596
    lenus@hse.ie | Tel: +353-1-7786275
    DSpace software copyright © 2002-2017  DuraSpace
    Contact Us | Disclaimer
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.