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    Illicit substance use and its correlates in first episode psychosis.

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    Authors
    Mazzoncini, R
    Donoghue, K
    Hart, J
    Morgan, C
    Doody, G A
    Dazzan, P
    Jones, P B
    Morgan, K
    Murray, R M
    Fearon, P
    Affiliation
    Department of Medicine and Public Health, University of Verona, Italy. rodolfo.mazzoncini@univr.it <rodolfo.mazzoncini@univr.it>
    Issue Date
    2010-05
    MeSH
    Acute Disease
    Adolescent
    Adult
    Age of Onset
    Comorbidity
    Cross-Cultural Comparison
    Cross-Sectional Studies
    England
    Female
    Humans
    Male
    Marijuana Abuse
    Middle Aged
    Psychoses, Substance-Induced
    Psychotic Disorders
    Retrospective Studies
    Social Adjustment
    Street Drugs
    Substance-Related Disorders
    Young Adult
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    Citation
    Illicit substance use and its correlates in first episode psychosis. 2010, 121 (5):351-8 Acta Psychiatr Scand
    Journal
    Acta psychiatrica Scandinavica
    URI
    http://hdl.handle.net/10147/128743
    DOI
    10.1111/j.1600-0447.2009.01483.x
    PubMed ID
    19824986
    Additional Links
    DOI: 10.1111/j.1600-0447.2009.01483.x
    Abstract
    To determine if substance use (particularly cannabis) is more frequent among first episode psychosis patients and associated with a more problematic clinical presentation.
    All first episode psychosis (FEP) patients presenting to secondary services were recruited from London and Nottingham, over 2 years, in the Aetiology and Ethnicity of Schizophrenia and Other Psychoses study broad framework. Clinical and sociodemographic variables were assessed using a set of standardized instruments. A schedule was created to retrospectively collate substance use data from patients, relatives and clinicians.
    Five hundred and eleven FEP were identified. They used three to five times more substances than general population. Substance use was associated with poorer social adjustment and a more acute mode of onset. Cannabis use did not affect social adjustment, but was associated with a more acute mode of onset.
    Cannabis has a different impact on FEP than other substances. Large epidemiological studies are needed to disentangle cannabis effect.
    Language
    en
    ISSN
    1600-0447
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1600-0447.2009.01483.x
    Scopus Count
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    St. Patrick's University Hospital

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