Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link.
dc.contributor.author | Conroy, H | |
dc.contributor.author | Mawhinney, L | |
dc.contributor.author | Donnelly, S C | |
dc.date.accessioned | 2011-04-18T09:05:53Z | |
dc.date.available | 2011-04-18T09:05:53Z | |
dc.date.issued | 2010-11 | |
dc.identifier.citation | Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link. 2010, 103 (11):831-6 QJM | en |
dc.identifier.issn | 1460-2393 | |
dc.identifier.pmid | 20805118 | |
dc.identifier.doi | 10.1093/qjmed/hcq148 | |
dc.identifier.uri | http://hdl.handle.net/10147/128251 | |
dc.description.abstract | Macrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression. | |
dc.language.iso | en | en |
dc.subject.mesh | Animals | |
dc.subject.mesh | Biological Markers | |
dc.subject.mesh | Cell Hypoxia | |
dc.subject.mesh | Disease Progression | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Inflammation | |
dc.subject.mesh | Macrophage Migration-Inhibitory Factors | |
dc.subject.mesh | Mice | |
dc.subject.mesh | Neoplasms | |
dc.subject.mesh | Neovascularization, Pathologic | |
dc.title | Inflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link. | en |
dc.type | Article | en |
dc.contributor.department | Conway Institute for Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland. | en |
dc.identifier.journal | QJM : monthly journal of the Association of Physicians | en |
refterms.dateFOA | 2018-08-22T12:02:22Z | |
html.description.abstract | Macrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression. |