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dc.contributor.authorConroy, H
dc.contributor.authorMawhinney, L
dc.contributor.authorDonnelly, S C
dc.date.accessioned2011-04-18T09:05:53Z
dc.date.available2011-04-18T09:05:53Z
dc.date.issued2010-11
dc.identifier.citationInflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link. 2010, 103 (11):831-6 QJMen
dc.identifier.issn1460-2393
dc.identifier.pmid20805118
dc.identifier.doi10.1093/qjmed/hcq148
dc.identifier.urihttp://hdl.handle.net/10147/128251
dc.description.abstractMacrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression.
dc.language.isoenen
dc.subject.meshAnimals
dc.subject.meshBiological Markers
dc.subject.meshCell Hypoxia
dc.subject.meshDisease Progression
dc.subject.meshHumans
dc.subject.meshInflammation
dc.subject.meshMacrophage Migration-Inhibitory Factors
dc.subject.meshMice
dc.subject.meshNeoplasms
dc.subject.meshNeovascularization, Pathologic
dc.titleInflammation and cancer: macrophage migration inhibitory factor (MIF)--the potential missing link.en
dc.typeArticleen
dc.contributor.departmentConway Institute for Biomolecular and Biomedical Research, School of Medicine and Medical Science, University College Dublin, Dublin 4, Ireland.en
dc.identifier.journalQJM : monthly journal of the Association of Physiciansen
refterms.dateFOA2018-08-22T12:02:22Z
html.description.abstractMacrophage migration inhibitory factor (MIF) was the original cytokine, described almost 50 years ago and has since been revealed to be an important player in pro-inflammatory diseases. Recent work using MIF mouse models has revealed new roles for MIF. In this review, we present an increasing body of evidence implicating the key pro-inflammatory cytokine MIF in specific biological activities related directly to cancer growth or contributing towards a microenvironment favouring cancer progression.


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