• Generalized subcutaneous edema as a rare manifestation of dermatomyositis: clinical lesson from a rare feature.

      Haroon, Muhammad; Eltahir, Ahmed; Harney, Sinead; Department of Rheumatology, Sports and Exercise Medicine, Cork University Hospital, Cork, Ireland. Mharoon301@hotmail.com (2011-04)
      Generalized subcutaneous edema is a very rare manifestation of inflammatory myopathies. A 61-year-old woman presented with classic signs and symptoms of dermatomyositis. She was also noted to have generalized edema that was so florid that an alternative diagnosis was considered. Her disease was resistant to corticosteroids, azathioprine, and mycophenolate mofetil. Intravenous administration of immunoglobulins was started because of marked worsening of her disease-muscle weakness, generalized anasarca, and involvement of her bulbar muscles. This led to dramatic resolution of her subcutaneous edema and significant improvement of her skin and muscle disease. As the initial screen for malignancy was negative, a positron emission tomography-computed tomography scan was requested, which interestingly showed a metabolically active cervical tumor. Anasarca is an unusual manifestation of dermatomyositis. In treatment-refractory cases, it seems reasonable to consider positron emission tomography scan in excluding underlying malignant disease.
    • The uptake of influenza and pneumococcal vaccination among immunocompromised patients attending rheumatology outpatient clinics.

      Haroon, Muhammad; Adeeb, Fahd; Eltahir, Ahmed; Harney, Sinead; Department of Rheumatology, Cork University Hospital, Cork, Ireland. mharoon301@hotmail.com (Elsevier, 2011-07)
      PURPOSE AND OBJECTIVES: The patients using immunosuppressive agents are considered at high risk for acquiring different infections. Accordingly, international guidelines recommend vaccinating such patients against influenza and pneumococcal organisms. The aims of this study were two-fold: (1) to assess the influenza and pneumococcal vaccination uptake among our rheumatology outpatients who are immunosuppressed; (2) to identify the factors influencing immunisation uptake among our sample of patients.