• Infants who required Therapeutic Hypothermia in Ireland, 2016-2017: lay summary

      National Perinatal Epidemiology Centre (Cork University Maternity Hospital, 2018)
      The National Clinical Programme Paediatrics and Neonatology (NCPPN) has identified a gap in the knowledge available nationally to clinicians and managers regarding TH. In 2017, a collaboration was agreed between the NCPPN and the National Perinatal Epidemiology Centre to examine the care of all infants who underwent TH in the years, 2016 and 2017. The primary aim of this report is to present an overview and national statistics on TH in Ireland for the years 2016 and 2017.
    • Neonatal Therapeutic Hypothermia in Ireland Annual Report 2016-2017

      Meaney, S; McGinley, J; Horkan, S; Corcoran, P; Greene, RA; Murphy, J; National Perinatal Epidemiology Centre Department of Obstetrics and Gynaecology University College Cork (National Perinatal Epidemiology Centre, 2018)
    • Perinatal factors affect the gut microbiota up to four years after birth.

      Fouhy, Fiona; Watkins, Claire; Hill, Cian J; O'Shea, Carol-Anne; Nagle, Brid; Dempsey, Eugene M; O'Toole, Paul W; Ross, R Paul; Ryan, C Anthony; Stanton, Catherine (2019-04-03)
      Perinatal factors impact gut microbiota development in early life, however, little is known on the effects of these factors on microbes in later life. Here we sequence DNA from faecal samples of children over the first four years and reveal a perpetual evolution of the gut microbiota during this period. The significant impact of gestational age at birth and delivery mode on gut microbiota progression is evident in the first four years of life, while no measurable effects of antibiotics are found in the first year. Microbiota profiles are also characteristic in children dependant on gestational age and maturity. Full term delivery is characterised by Bacteroides (year one), Parabacteroides (year two) and Christensenellaceae (year four). Preterm delivery is characterised by Lactobacillus (year one), Streptococcus (year two) and Carnobacterium (year four). This study reveals that the gut retains distinct microbial profiles of perinatal factors up to four years of age.