• The value of metabolic markers in diagnosis of vitamin 12 deficiency

      Deverrill, D; Fitzsimons PE; Macken, S; Crushell, E; McMahon, C; Mayne, PD; Rotunda Hospital (2009-10)
    • The value of neonatal autopsy.

      Hickey, Leah; Murphy, Amanda; Devaney, Deirdre; Gillan, John; Clarke, Tom; Rotunda Hospital, Dublin, Ireland. leahmariahickey@yahoo.co.uk (2012)
      Neonatal autopsy rates were in decline internationally at the end of the last century. Our objective was to assess the current value of neonatal autopsy in providing additional information to families and healthcare professionals.
    • Viral screening at the time of each donation in ART patients: is it justified?

      Hughes, C; Grundy, K; Emerson, G; Mocanu, E; Human Assisted Reproduction Ireland, Rotunda Hospital, Dublin 1, Dublin. chughes@rcsi.ie (2011-11)
      The frequency for virology testing for couples undergoing assisted reproductive treatment (ART) in Europe is currently under debate, with little scientific data available to support the time-frame imposed by EU legislation. The aim of this study was to determine the incidence of blood-borne viruses (BBV) in this population and to assess the likelihood of seroconversion after an initial negative screen and the possible cost saving to couples.
    • What is new in obstetric antecedents of chronic disease? Best articles from the past year.

      Malone, Fergal D; Rotunda Hospital (2014-04)
      This month, we focus on current research in obstetric antecedents of chronic disease. Dr Malone discusses four recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page along with direct links to the abstracts.
    • When no choice of embryos exists, the multiple pregnancy risk is still high.

      Wong, V V; Emerson, G; Mocanu, E; Human Assisted Reproduction Ireland, Rotunda Hospital, Dublin, Republic of Ireland. vuivunwong@yahoo.com (2012-10)
      Multiple pregnancies arising from assisted reproduction are known to be associated with increased medical, psychological, economical and social risks. If only two embryos develop after culture, how should the couple be counselled in relation to the risk of multiple pregnancy? We performed a retrospective review of all IVF/ICSI treatments performed between 1 January 2005 and 31 December 2007, that resulted in double embryos transfer (DET). We identified 623 cycles with a fortuitous DET (Group I) and 635 cycles with an elective DET (Group II). Group II were significantly more likely to have twins when compared with Group I, irrespective of age. Twin rates in Group I were higher in IVF compared with ICSI; 33.3% vs 16.6% in < 35 years old and 16.2% vs 7.6% in 35-40 years old. Therefore, single embryo transfer should be considered for IVF patients below 35 years old, even if only two good quality embryos are available.