• HIE at the Rotunda: 2 years review of babies who fulfil the criteria for cooling

      Mustafa, N; King, M; Hayes, B; Foran, A; Rotunda Hospital (2009)
    • HIV testing and treatment in the antenatal care setting.

      Coulter-Smith, S; Lambert, J S; Butler, K; Brennan, M; Cafferkey, M; The Rotunda Hospital, Parnell Sq, Dublin 1. (2012-02-01)
      Routine linked HIV antenatal screening, with "opt-out", was introduced at the Rotunda in January 1998. This paper reviews the screening and subsequent pregnancy management and outcome in HIV positive women from 1998 to 2006. During this time 225 women (280 pregnancies) were HIV positive and 194 women subsequently delivered at the Rotunda, representing 233 liveborn infants. Overall anti-HIV prevalence was 0.42%, increasing from 0.06% in 1998 to 0.57% in 2006. Of 233 livebirths, 111 (48%) were delivered by spontaneous vaginal delivery (SVD). HIV treatment was started pre-pregnancy in 14 (6%) pregnancies and antenatally in 208 (90%). The vertical transmission rate in mothers receiving >4 weeks of treatment was 0%. We conclude that routine antenatal HIV screening is effective and significantly benefits the health of mother and child.
    • How effective is amniotomy as a means of induction of labour?

      Cooley, S M; Geary, M P; O'Connell, M P; McQuillan, K; McParland, P; Keane, D; Rotunda Hospital, Parnell Square, Dublin 1, Ireland. smcooley@hotmail.com (2012-02-01)
      BACKGROUND: Amniotomy or artificial rupture of membranes is routinely used for induction of labour. AIMS: To assess the efficacy of amniotomy alone for induction. METHODS: A retrospective descriptive study of 3,586 cases of amniotomy for induction of labour between July 1996 and December 1999. RESULTS: In total, 26,670 women delivered in the National Maternity Hospital during the study period. Of these 4,928 women required induction of labour and 72.8% of these (n = 3,586) underwent amniotomy only for induction of labour. Spontaneous labour occurred in 90.1% of the women who underwent amniotomy within 24 h. Oxytocin as an induction agent was employed in 9.8% of cases. Overall, 80.5% of the women had a spontaneous delivery, 7.3% had a ventouse delivery, 4.3% had a forceps delivery, and 7.9% underwent a caesarean section. In total, 90.5% of multips and 63.4% of primips had a spontaneous vaginal delivery. CONCLUSIONS: Amniotomy is a simple, safe and effective method of induction of labour.
    • How effective is amniotomy as a means of induction of labour?

      Cooley, S M; Geary, M P; O'Connell, M P; McQuillan, K; McParland, P; Keane, D; Rotunda Hospital, Parnell Square, Dublin 1, Ireland. smcooley@hotmail.com (2010-09)
      Amniotomy or artificial rupture of membranes is routinely used for induction of labour.
    • How safe is vaginal twin birth? Evidence from the prospective ESPRiT study

      Kent, E; Daly, S; Higgins, J; Burke, G; Morrison, J; Higgins, S; O'Malley, A; Geary, M; Dicker, P; Manning, F; et al. (Mosby Inc., 2011-01)
    • How the autopsy can explain over ninety percent of perinatal deaths

      Gillan, John Dr.; Rotunda Hospital (European Society of Pathology, 2009-09)
    • How to write an abstract that will be accepted.

      Higgins, M; Eogan, M; O Donoghue, K; Russell, N (2014-09-17)
    • Hypotension in preterm infants (HIP Study)

      Corcoran, David; Rotunda Hospital (2013-03)
    • Hypothermia in the newborn: an exploration of its cause, effect and prevention.

      Villinski, Aliona; Sheridan, Ann; Rotunda Hospital (2014-08-21)
    • Impact of adjusting for the reciprocal relationship between maternal weight and free thyroxine during early pregnancy.

      Haddow, James E; Craig, Wendy Y; Palomaki, Glenn E; Neveux, Louis M; Lambert-Messerlian, Geralyn; Canick, Jacob A; Malone, Fergal D; D'Alton, Mary E; Division of Medical Screening and Special Testing, Women and Infants Hospital, Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA. jhaddow@ipmms.org (2013-02)
      Among euthyroid pregnant women in a large clinical trial, free thyroxine (FT4) measurements below the 2.5th centile were associated with a 17 lb higher weight (2.9 kg/m(2)) than in the overall study population. We explore this relationship further.
    • Impact of birthweight discordance and of non-vertex presentation of the second twin on successful vaginal birth – The Esprit Trial [poster]

      Breathnach, F M; Carroll, S.; McAuliffe, A; Geary, M; Daly, S; Higgins, John R.; Dornan, J; Morrisson, J; Burke, G; Higgins, S.; et al. (Mosby Inc., 2009-12)
    • Impact of Introduction of a Clinical Pathway for the Management of Pyelonephritis on Obstetric Patients: a Quality Improvement Project

      Clooney, L; Ronayne, A; Glennon, K; Brennan, M; Hickey, N; Magee, C; Cooley, S; Eogan, M; Drew, R.J (Irish Medical Journal, 2019-06)
      Acute pyelonephritis is one of the most common medical complications of pregnancy. It occurs in 0.5–2% of pregnant women and can result in significant maternal and fetal morbidity1,2. Additionally there is a financial burden on the hospital due to prolonged inpatient stays, increased preterm birth rate and associated neonatal care 3. Although there have been many studies evaluating the benefit of treating asymptomatic bacteriuria to prevent pyelonephritis in pregnancy, there is little recent evidence around how to treat pyelonephritis in pregnancy 4-6. In 1995 a study was published which showed the benefit of ceftriaxone in pregnancy, when compared to cefazolin but did not address issues such as prophylaxis during the remaining pregnancy and need for additional gentamicin
    • The impact of positive acquired thrombophilia serology on ultrasound, obstetric outcome and the placenta in low risk primagravid population

      Cooley, Sharon M, Donnelly, Jennifer C, Walsh, Thomas, Collins, Claire, McMahon, Corrina, Gillan, John and Geary Michael P.; Rotunda Hospital , Dublin. (Springer Verlag, 2011-03)
    • The impact of ultrasonographic placental architecture on antenatal course, labor and delivery in a low-risk primigravid population.

      Cooley, Sharon M; Donnelly, Jennifer C; Walsh, Thomas; McMahon, Corrina; Gillan, John; Geary, Michael P; Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland., smcooley@hotmail.com (2012-02-01)
      OBJECTIVE: To ascertain the impact of placental architecture on antenatal course and labor delivery in a low-risk primigravid population. METHODS: This study involves prospective recruitment of 1011 low-risk primigravids with placental ultrasound at 22?24 weeks and 36 weeks. Detailed postnatal review of all mothers and infants was undertaken. Retrospective analysis of ultrasound and clinical outcome data was performed. RESULTS: Eight hundred ten women with complete outcome data were available. Anterior placentation was statistically associated with intrauterine growth restriction (IUGR) and preterm birth and fundal placentation was significantly associated with a higher incidence of pregnancy-induced hypertension and infants with a birthweight less than the 9th centile. Placental infarcts in the third trimester was significantly increased in cases complicated by pre-eclampsia (PET) and in cases with fetal acidosis. Placental calcification was associated a 40-fold increase in the incidence of IUGR. Placental lakes in the second trimester were more prevalent in patients with threatened miscarriage. Increased placental thickness was associated with a higher rate of fetal acidosis. The Grannum grade of the placenta was higher with threatened first or second trimester loss, PET and in infants born less than 9th centile for gestation. CONCLUSION: Placental site and architecture impact on the incidence of maternal and fetal disease.
    • The impact of ultrasonographic placental architecture on antenatal course, labor and delivery in a low-risk primigravid population.

      Cooley, Sharon M; Donnelly, Jennifer C; Walsh, Thomas; McMahon, Corrina; Gillan, John; Geary, Michael P; Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland. smcooley@hotmail.com (2011-03)
      To ascertain the impact of placental architecture on antenatal course and labor delivery in a low-risk primigravid population.
    • The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population.

      Cooley, Sharon M; Donnelly, Jennifer C; Walsh, Thomas; MacMahon, Corrina; Gillan, John; Geary, Michael P; Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland., smcooley@hotmail.com (2012-02-01)
      AIMS: To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population. METHODS: Prospective recruitment of 1011 low-risk primigravidas with uterine and umbilical artery Doppler assessment at 22-24 weeks and 36 weeks. All mothers and infants were reviewed postnatally with a retrospective analysis of ultrasound and clinical outcome data. RESULTS: Elevated uterine artery indices were associated with increased rates of threatened miscarriage, higher rates of pre-eclampsia (PET) and a higher incidence of fetal birth weight <2nd and 9th centile for gestation. Uterine artery pulsatility index (PI) >95th centile for gestation was associated with statistically higher rates of small-for-gestational age (SGA) infants. Elevated umbilical artery indices were associated with higher rates of induction of labor and a higher incidence of fetal birth weight infants <2nd and 9th centile for gestation. Umbilical artery PI >95th centile for gestation was associated with statistically higher rates of SGA infants. CONCLUSION: Elevated uterine and umbilical artery indices are associated with higher rates of maternal and fetal disease.
    • The impact of umbilical and uterine artery Doppler indices on antenatal course, labor and delivery in a low-risk primigravid population.

      Cooley, Sharon M; Donnelly, Jennifer C; Walsh, Thomas; MacMahon, Corrina; Gillan, John; Geary, Michael P; Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin 1, Ireland. smcooley@hotmail.com (2011-03)
      To evaluate the impact of umbilical and uterine artery Doppler in the second and third trimester on antenatal course, labor and delivery in a low-risk primigravid population.
    • Impaired glucose metabolism in HIV 1 seropositive pregnant women: a prospective study

      Rock, C; Kyithar, V; Jackson, M; Brennan, M; Eogan, J; Edwards, A; Fleming, M; Byrne, J; Lambert, J (2011)
    • Impaired glucose metabolism in HIV-infected pregnant women: a retrospective analysis.

      Moore, Rebecca; Adler, Hugh; Jackson, Valerie; Lawless, Mairead; Byrne, Maria; Eogan, Maeve; Lambert, John S; Rotunda Hospital Dublin (2015-05-20)
      Metabolic complications including diabetes mellitus have been increasingly recognised in HIV-infected individuals since the introduction of antiretroviral therapy, particularly protease inhibitors (PIs). Pregnancy is also a risk factor for impaired glucose metabolism, and previous studies have given conflicting results regarding the contribution of PIs to impaired glucose tolerance (IGT) and gestational diabetes mellitus (GDM) in pregnant HIV-infected women.