• Does the Endometrial Scratch improve implantation rates?

      Chawla, S; Purandare, N; Mocanu, E; Hughe, C; Deignan, K; Naasan, M; Kirkham, C (Irish Medical Journal, 2015-07)
      Implantation is one of the most crucial steps in the process of reproduction. Implantation failure is often due to impaired uterine receptivity. Assisted Reproduction techniques are used in order to overcome fertility problems. The endometrial scratch (ES) is a relatively new technique that is said to improve the probability of a successful pregnancy in some women. 1 Although the exact mechanism of this process is still unknown 2 , the use of a catheter to cause local injury to the endometrial lining is suggested to initiate a healing process, thereby attracting immune markers and potentially improving implantation rates. The aim of this study is to assess whether the ES offered randomly to patients attending for ART results in a higher implantation rate in patients that avail of it compared to patients that do not have an endometrial scratch (non-ES).
    • Grieving After Early Pregnancy Loss - A Common Reality

      Purandare, N; Ryan, G; Ciprike, V; Trevisan, J; Sheehan, J; Geary, M (Irish Medical Journal, 2012-12)
    • Grieving after early pregnancy loss--a common reality.

      Purandare, N; Ryan, G; Ciprike, V; Trevisan, J; Sheehan, J; Geary, M; Rotunda Hospital, Parnell St, Dublin 1. docnikhilp@rediffmail.com (2013-05-24)
      A miscarriage can be very traumatic for a couple and their immediate family. The aim of this study was to assess, using the Perinatal Grief Scale (PGS), whether the type of early pregnancy loss influences the severity of grief and whether the presence of living children influences the severity of grief. Over a period of 6 months in 2008, seventy five patients were recruited for the study, of which 7 (9.3%) had molar pregnancies, 20 (26.7%) had ectopic pregnancies, 43 (573%) had a miscarriage and 5 (6.7%) had recurrent miscarriages. In this study there was no significant difference in severity of grief, between women that had a miscarriage and ectopic pregnancy (p = 0.14) or, between women that had a miscarriage and a molar pregnancy (p = 0.85). Women who had experienced a ectopic pregnancy did not have a higher grief intensity than the women that had a molar pregnancy (p = 0.75). However, for women with a child, the grief intensity significantly increases with the number of miscarriages (p = 0.015). Women with no children with an ectopic pregnancy grieve significantly more than those with a child (p = 0.019). An appointment for the 'Miscarriage Clinic' should be offered to all of these women but special attention should be paid to those in the categories most at risk
    • Grieving after early pregnancy loss: a common reality.

      Purandare, N; Ryan, G; Ciprike, V; Trevison, J; Sheehan, J; Geary, M (2013-02-22)
    • Perinatal outcome after ultrasound diagnosis of anhydramnios at term.

      Visvalingam, G; Purandare, N; Cooley, S; Roopnarinesingh, R; Geary, M; Department of Obstetrics and Gynaecology, Rotunda Hospital, Dublin, Ireland. geethavisva@yahoo.com (2012-01)
      The aim was to assess the maternal and fetal outcome in women who had labour induced for anhydramnios after 37 completed weeks of gestation. A retrospective study was conducted at the Rotunda Hospital from 1 January 2003 to 31 December 2007. All women with anhydramnios at term were identified from a review of ViewPoint® (computer software for antenatal scans performed), hospital data and the labour ward register. All women with a history of previous lower segment caesarean section (LSCS), current significant medical illness such as diabetes, hypertension, pre-eclampsia or ruptured membranes were excluded because the aim of the study was to focus specifically on low risk pregnancies with an incidental diagnosis of anhydramnios after 37 weeks' gestation. The maternal and fetal outcome parameters reviewed included: maternal age, parity, gestation, method of induction, mode of delivery, Apgar score and the requirement for obstetric or neonatal intervention. This study showed that anhydramnios is associated with a 56.6% LSCS rate in primigravida and a 19.0% LSCS rate in multigravida. Our study did not show any significant neonatal morbidity and there were no cases of mortality.
    • Perinatal outcome after ultrasound diagnosis of anhydramnios at term.

      Visvalingam, G,; Purandare, N; Cooley, S; Roopnarinesingh, R; Geary, M (2013-02-22)
    • Ruptured broad ligament ectopic gestation in a Jehovah's Witness with a negative pregnancy test

      Maayeh, M; Purandare, N; Flanagan, N; Ash, S; Geary, M; Breathnach FM (2014-09-22)