• High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation.

      O'Malley, G; Santoro, N; Northrup, V; D'Adamo, E; Shaw, M; Eldrich, S; Caprio, S; Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, PO Box 208064, New Haven, CT 06520, USA. (2010-06)
      These data suggest that in obese youth, independent of age, BMI z score, sex, family history and ethnicity, insulin sensitivity and secretion decline when moving from low to high normal fasting plasma glucose. The simple measure of fasting plasma glucose could assist clinicians in identifying children for targeted diabetes screening and subsequent lifestyle management.