• High normal fasting glucose level in obese youth: a marker for insulin resistance and beta cell dysregulation.

      O'Malley, G; Santoro, N; Northrup, V; D'Adamo, E; Shaw, M; Eldrich, S; Caprio, S; Department of Pediatrics, Yale University School of Medicine, 330 Cedar Street, PO Box 208064, New Haven, CT 06520, USA. (2010-06)
      A high but normal fasting plasma glucose level in adults is a risk factor for future development of type 2 diabetes mellitus and cardiovascular disease. We investigated whether normal fasting plasma glucose levels (<5.60 mmol/l) are associated with decreases in insulin sensitivity and beta cell function, as well as an adverse cardiovascular profile in obese youth.