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    The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial.

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    Authors
    McDonnell, John G
    O'Donnell, Brian
    Curley, Gerard
    Heffernan, Anne
    Power, Camillus
    Laffey, John G
    Affiliation
    Department of Anaesthesia and Intensive Care Medicine, University College Hospital, Galway, Ireland.
    Issue Date
    2007-01
    MeSH
    Abdomen
    Analgesia
    Double-Blind Method
    Female
    Humans
    Intestine, Large
    Intestines
    Male
    Middle Aged
    Neuromuscular Depolarizing Agents
    Pain, Postoperative
    Surgical Procedures, Operative
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    Citation
    The analgesic efficacy of transversus abdominis plane block after abdominal surgery: a prospective randomized controlled trial. 2007, 104 (1):193-7 Anesth. Analg.
    Journal
    Anesthesia and analgesia
    URI
    http://hdl.handle.net/10147/127916
    DOI
    10.1213/01.ane.0000250223.49963.0f
    PubMed ID
    17179269
    Abstract
    The transversus abdominis plane (TAP) block is a novel approach for blocking the abdominal wall neural afferents via the bilateral lumbar triangles of Petit. We evaluated its analgesic efficacy in patients during the first 24 postoperative hours after abdominal surgery, in a randomized, controlled, double-blind clinical trial.
    Thirty-two adults undergoing large bowel resection via a midline abdominal incision were randomized to receive standard care, including patient-controlled morphine analgesia and regular nonsteroidal antiinflammatory drugs and acetaminophen (n = 16), or to undergo TAP block (n = 16) in addition to standard care (n = 16). After induction of anesthesia, 20 mL of 0.375% levobupivacaine was deposited into the transversus abdominis neuro-fascial plane via the bilateral lumbar triangles of Petit. Each patient was assessed by a blinded investigator in the postanesthesia care unit and at 2, 4, 6, and 24 h postoperatively.
    The TAP block reduced visual analog scale pain scores (TAP versus control, mean +/- sd) on emergence (1 +/- 1.4 vs 6.6 +/- 2.8, P < 0.05), and at all postoperative time points, including at 24 h (1.7 +/- 1.7 vs 3.1 +/- 1.5, P < 0.05). Morphine requirements in the first 24 postoperative hours were also reduced (21.9 +/- 8.9 mg vs 80.4 +/- 19.2 mg, P < 0.05). There were no complications attributable to the TAP block. All TAP patients reported high levels of satisfaction with their postoperative analgesic regimen.
    The TAP block provided highly effective postoperative analgesia in the first 24 postoperative hours after major abdominal surgery.
    Item Type
    Article
    Language
    en
    ISSN
    1526-7598
    ae974a485f413a2113503eed53cd6c53
    10.1213/01.ane.0000250223.49963.0f
    Scopus Count
    Collections
    Galway University Hospitals

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