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    Early aggressive intra-venous pulse cyclophosphamide therapy for interstitial lung disease in a patient with systemic sclerosis. A case report.

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    Authors
    Peshin, R
    O'Neill, L
    Browne, P
    O'Connell, P
    Kearns, G
    Affiliation
    Department of Rheumatology, Beaumont Hospital, Dublin, Republic of Ireland. rohit_peshin@yahoo.com
    Issue Date
    2009-06
    MeSH
    Anti-Inflammatory Agents
    Antineoplastic Agents, Alkylating
    Cyclophosphamide
    Humans
    Infusions, Intravenous
    Lung Diseases, Interstitial
    Male
    Middle Aged
    Prednisolone
    Scleroderma, Systemic
    
    Metadata
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    Citation
    Early aggressive intra-venous pulse cyclophosphamide therapy for interstitial lung disease in a patient with systemic sclerosis. A case report. 2009, 28 Suppl 1:S31-4 Clin. Rheumatol.
    Journal
    Clinical rheumatology
    URI
    http://hdl.handle.net/10147/127651
    DOI
    10.1007/s10067-009-1098-y
    PubMed ID
    19194736
    Abstract
    Interstitial lung disease is an important cause of mortality and morbidity in patients with systemic sclerosis (SSc). There are currently no recommended guidelines for management of these patients. This is probably due to the rarity of this condition, as well as clinical trials with only a small number of cases. There are published case report and case series along with the two main trials, viz. Scleroderma Lung Study and the Fibrosing Alveolitis Study, but again, there is no consensus on treatment protocols. In this report, we present a case of aggressive interstitial lung disease in a patient with SSc, which improved dramatically on treatment with intra-venous cyclophosphamide and high dose prednisolone therapy.
    Item Type
    Article
    Language
    en
    ISSN
    1434-9949
    ae974a485f413a2113503eed53cd6c53
    10.1007/s10067-009-1098-y
    Scopus Count
    Collections
    Beaumont Hospital

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