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dc.contributor.authorPhukan, Julie
dc.contributor.authorHardiman, Orla
dc.date.accessioned2011-04-07T08:54:45Z
dc.date.available2011-04-07T08:54:45Z
dc.date.issued2009-02
dc.identifier.citationThe management of amyotrophic lateral sclerosis. 2009, 256 (2):176-86 J. Neurol.en
dc.identifier.issn1432-1459
dc.identifier.pmid19224316
dc.identifier.doi10.1007/s00415-009-0142-9
dc.identifier.urihttp://hdl.handle.net/10147/127637
dc.description.abstractThe terms amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) refer to a condition characterized by motor system degeneration with relative preservation of other pathways. Although there have been advances in symptomatic treatment, ALS remains an incurable condition. Advances in ALS management prolong survival but simultaneously raise challenging ethical dilemmas for physicians, patients and their families. Here, we review current practice in the management of ALS including pharmacological treatment, nutritional management, respiratory care, and evolving strategies in the management of cognitive impairment.
dc.language.isoenen
dc.subject.meshAmyotrophic Lateral Sclerosis
dc.subject.meshCaregivers
dc.subject.meshCognition Disorders
dc.subject.meshGenetic Predisposition to Disease
dc.subject.meshLong-Term Care
dc.subject.meshPalliative Care
dc.subject.meshPhysician-Patient Relations
dc.subject.meshRespiration, Artificial
dc.subject.meshRespiratory Insufficiency
dc.subject.meshWithholding Treatment
dc.titleThe management of amyotrophic lateral sclerosis.en
dc.typeArticleen
dc.contributor.departmentDept. of Neurology, Beaumont Hospital, and Trinity College Institute of Neuroscience, Dublin 9, Ireland.en
dc.identifier.journalJournal of neurologyen
dc.description.provinceLeinster
html.description.abstractThe terms amyotrophic lateral sclerosis (ALS) or motor neuron disease (MND) refer to a condition characterized by motor system degeneration with relative preservation of other pathways. Although there have been advances in symptomatic treatment, ALS remains an incurable condition. Advances in ALS management prolong survival but simultaneously raise challenging ethical dilemmas for physicians, patients and their families. Here, we review current practice in the management of ALS including pharmacological treatment, nutritional management, respiratory care, and evolving strategies in the management of cognitive impairment.


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