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dc.contributor.authorJaneczko, Cassandra
dc.contributor.authorMcHugh, John
dc.contributor.authorRawluk, Daniel
dc.contributor.authorFarrell, Michael
dc.contributor.authorBrennan, Paul
dc.contributor.authorDelanty, Norman
dc.date.accessioned2011-04-07T08:54:02Z
dc.date.available2011-04-07T08:54:02Z
dc.date.issued2009-04
dc.identifier.citationHypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis. 2009, 16 (4):599-600 J Clin Neuroscien
dc.identifier.issn0967-5868
dc.identifier.pmid19231195
dc.identifier.doi10.1016/j.jocn.2008.04.031
dc.identifier.urihttp://hdl.handle.net/10147/127636
dc.description.abstractHypophysitis secondary to a ruptured Rathke's cyst is rare. We describe a 53-year-old female who presented with headache and subsequently developed aseptic meningitis and panhypopituitarism. MRI findings and concomitant cardiac arrhythmia and peripheral vasculitis led to a provisional diagnosis of neurosarcoidosis. There were no respiratory manifestations of sarcoidosis. Improvement was noted with empirical treatment with steroids. Pituitary biopsy was undertaken to confirm the diagnosis prior to treatment with long-term immunosuppression for putative neurosarcoidosis. The biopsy revealed lymphocytic hypophysitis secondary to a ruptured Rathke's cyst. This report highlights a rare pathology and the importance of a tissue diagnosis before undertaking non-surgical management of a pituitary mass.
dc.language.isoenen
dc.subject.meshAneurysm, Ruptured
dc.subject.meshCentral Nervous System Cysts
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMagnetic Resonance Imaging
dc.subject.meshMiddle Aged
dc.subject.meshPituitary Diseases
dc.subject.meshTomography, X-Ray
dc.titleHypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis.en
dc.typeArticleen
dc.contributor.departmentDepartment of Neurology, Beaumont Hospital, P.O. Box 1297, Beaumont Road, Dublin 9, Ireland. cejaneczko@hotmail.comen
dc.identifier.journalJournal of clinical neuroscience : official journal of the Neurosurgical Society of Australasiaen
dc.description.provinceLeinster
html.description.abstractHypophysitis secondary to a ruptured Rathke's cyst is rare. We describe a 53-year-old female who presented with headache and subsequently developed aseptic meningitis and panhypopituitarism. MRI findings and concomitant cardiac arrhythmia and peripheral vasculitis led to a provisional diagnosis of neurosarcoidosis. There were no respiratory manifestations of sarcoidosis. Improvement was noted with empirical treatment with steroids. Pituitary biopsy was undertaken to confirm the diagnosis prior to treatment with long-term immunosuppression for putative neurosarcoidosis. The biopsy revealed lymphocytic hypophysitis secondary to a ruptured Rathke's cyst. This report highlights a rare pathology and the importance of a tissue diagnosis before undertaking non-surgical management of a pituitary mass.


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