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    Hypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis.

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    Authors
    Janeczko, Cassandra
    McHugh, John
    Rawluk, Daniel
    Farrell, Michael
    Brennan, Paul
    Delanty, Norman
    Affiliation
    Department of Neurology, Beaumont Hospital, P.O. Box 1297, Beaumont Road, Dublin 9, Ireland. cejaneczko@hotmail.com
    Issue Date
    2009-04
    MeSH
    Aneurysm, Ruptured
    Central Nervous System Cysts
    Female
    Humans
    Magnetic Resonance Imaging
    Middle Aged
    Pituitary Diseases
    Tomography, X-Ray
    
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    Citation
    Hypophysitis secondary to ruptured Rathke's cyst mimicking neurosarcoidosis. 2009, 16 (4):599-600 J Clin Neurosci
    Journal
    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
    URI
    http://hdl.handle.net/10147/127636
    DOI
    10.1016/j.jocn.2008.04.031
    PubMed ID
    19231195
    Abstract
    Hypophysitis secondary to a ruptured Rathke's cyst is rare. We describe a 53-year-old female who presented with headache and subsequently developed aseptic meningitis and panhypopituitarism. MRI findings and concomitant cardiac arrhythmia and peripheral vasculitis led to a provisional diagnosis of neurosarcoidosis. There were no respiratory manifestations of sarcoidosis. Improvement was noted with empirical treatment with steroids. Pituitary biopsy was undertaken to confirm the diagnosis prior to treatment with long-term immunosuppression for putative neurosarcoidosis. The biopsy revealed lymphocytic hypophysitis secondary to a ruptured Rathke's cyst. This report highlights a rare pathology and the importance of a tissue diagnosis before undertaking non-surgical management of a pituitary mass.
    Item Type
    Article
    Language
    en
    ISSN
    0967-5868
    ae974a485f413a2113503eed53cd6c53
    10.1016/j.jocn.2008.04.031
    Scopus Count
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    Beaumont Hospital

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