Malignant melanoma and breast carcinoma: a bidirectional correlation.
| dc.contributor.author | Ho, W L | |
| dc.contributor.author | Comber, H | |
| dc.contributor.author | Hill, A D K | |
| dc.contributor.author | Murphy, G M | |
| dc.date.accessioned | 2011-04-07T08:52:48Z | |
| dc.date.available | 2011-04-07T08:52:48Z | |
| dc.date.issued | 2009-03-05 | |
| dc.identifier.citation | Malignant melanoma and breast carcinoma: a bidirectional correlation. 2009: Ir J Med Sci | en |
| dc.identifier.issn | 1863-4362 | |
| dc.identifier.pmid | 19263184 | |
| dc.identifier.doi | 10.1007/s11845-009-0297-5 | |
| dc.identifier.uri | http://hdl.handle.net/10147/127624 | |
| dc.description.abstract | BACKGROUND: Epidemiologic and genetic studies have suggested a bidirectional association between breast carcinoma (BC) and malignant melanoma (MM). OBSERVATION: We present a series of patients with MM and BC detected in our department within a span of 6 months, raising concerns for the high associations between the two malignancies. This led us to match the concordance of the two tumours in the National Irish Cancer Registry. CONCLUSION: The national figures provide evidence of a link between BC and MM. We recommend increased awareness among clinicians leading to more detailed surveillance of both second primary tumours. All MM patients with a family history of BC should be referred to a breast clinic. Women above the age of 40 with MM should undergo annual mammography and those less than 40 may be better evaluated with a breast MRI. All breast cancer patients should be made aware of the significance of changing moles and those with suspicious lesions referred to a dermatologist for evaluation. | |
| dc.language | ENG | |
| dc.title | Malignant melanoma and breast carcinoma: a bidirectional correlation. | en |
| dc.type | Article In Press | en |
| dc.contributor.department | Department of Dermatology, Beaumont Hospital, Dublin 9, Ireland, drwlho@yahoo.com. | en |
| dc.identifier.journal | Irish journal of medical science | en |
| dc.description.province | Leinster | |
| html.description.abstract | BACKGROUND: Epidemiologic and genetic studies have suggested a bidirectional association between breast carcinoma (BC) and malignant melanoma (MM). OBSERVATION: We present a series of patients with MM and BC detected in our department within a span of 6 months, raising concerns for the high associations between the two malignancies. This led us to match the concordance of the two tumours in the National Irish Cancer Registry. CONCLUSION: The national figures provide evidence of a link between BC and MM. We recommend increased awareness among clinicians leading to more detailed surveillance of both second primary tumours. All MM patients with a family history of BC should be referred to a breast clinic. Women above the age of 40 with MM should undergo annual mammography and those less than 40 may be better evaluated with a breast MRI. All breast cancer patients should be made aware of the significance of changing moles and those with suspicious lesions referred to a dermatologist for evaluation. |