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    Malignant melanoma and breast carcinoma: a bidirectional correlation.

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    Authors
    Ho, W L
    Comber, H
    Hill, A D K
    Murphy, G M
    Affiliation
    Department of Dermatology, Beaumont Hospital, Dublin 9, Ireland, drwlho@yahoo.com.
    Issue Date
    2009-03-05
    
    Metadata
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    Citation
    Malignant melanoma and breast carcinoma: a bidirectional correlation. 2009: Ir J Med Sci
    Journal
    Irish journal of medical science
    URI
    http://hdl.handle.net/10147/127624
    DOI
    10.1007/s11845-009-0297-5
    PubMed ID
    19263184
    Abstract
    BACKGROUND: Epidemiologic and genetic studies have suggested a bidirectional association between breast carcinoma (BC) and malignant melanoma (MM). OBSERVATION: We present a series of patients with MM and BC detected in our department within a span of 6 months, raising concerns for the high associations between the two malignancies. This led us to match the concordance of the two tumours in the National Irish Cancer Registry. CONCLUSION: The national figures provide evidence of a link between BC and MM. We recommend increased awareness among clinicians leading to more detailed surveillance of both second primary tumours. All MM patients with a family history of BC should be referred to a breast clinic. Women above the age of 40 with MM should undergo annual mammography and those less than 40 may be better evaluated with a breast MRI. All breast cancer patients should be made aware of the significance of changing moles and those with suspicious lesions referred to a dermatologist for evaluation.
    Item Type
    Article In Press
    ISSN
    1863-4362
    ae974a485f413a2113503eed53cd6c53
    10.1007/s11845-009-0297-5
    Scopus Count
    Collections
    Beaumont Hospital

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